San Diego, CALIFORNIA7 Active Studies

Breast Cancer Clinical Trials in San Diego, CALIFORNIA

Find 7 actively recruiting breast cancer clinical trials in San Diego, CALIFORNIA. Connect with local research sites and explore new treatment options.

7
Active Trials
6
Sponsors
2,028
Enrolling

Recruiting Breast Cancer Studies in San Diego

RecruitingSan Diego, CALIFORNIANCT05150691

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1303/BNT323 in subjects with advanced solid tumors that express HER2....

796 participants
DualityBio Inc.
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RecruitingSan Diego, CALIFORNIANCT06324357

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

This study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery. People can take part in this study if their tumours show HER...

582 participants
Boehringer Ingelheim
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RecruitingSan Diego, CALIFORNIANCT05856773

Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy

The purpose of this research study is to learn more about the effects of using proton radiation therapy delivered over a shorter course of treatment (3 weeks) compared with a longer, standard course o...

276 participants
Proton Collaborative Group
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RecruitingSan Diego, CALIFORNIANCT01766297

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

The purpose of this research study is to compare the effects (good and bad) on women and their cancer using proton radiation therapy. This study is being done to see if proton radiation therapy will ...

132 participants
Proton Collaborative Group
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RecruitingSan Diego, CALIFORNIANCT06764940

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

This study is a multicenter, two-stage clinical trial to evaluate the efficacy and safety of utidelone in combination with capecitabine in patients with HER2-negative breast cancer with brain metastas...

120 participants
Biostar Pharma, Inc.
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RecruitingSan Diego, CALIFORNIANCT06126276

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

This phase II ComboMATCH treatment trial compares the effect of neratinib to the combination of neratinib and palbociclib in treating patients with HER2 positive solid tumors. Neratinib and palbocicli...

70 participants
National Cancer Institute (NCI)
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RecruitingSan Diego, CALIFORNIANCT05455619

Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

This is a Phase 1b/2, open-label, parallel-arms pilot study in men and post-menopausal women with hormone receptor positive (HR+), HER2- advanced or metastatic breast cancer with an alteration in the ...

52 participants
SynDevRx, Inc.
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About Breast Cancer Clinical Trials in San Diego

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 7 breast cancer clinical trials recruiting participants in San Diego, CALIFORNIA. These studies are seeking a combined 2,028 participants. Research is being sponsored by DualityBio Inc., Boehringer Ingelheim, Proton Collaborative Group and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in San Diego — FAQ

Are there breast cancer clinical trials in San Diego?

Yes, there are 7 breast cancer clinical trials currently recruiting in San Diego, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Diego?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you about next steps.

Are clinical trials in San Diego free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Diego studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 7 active trials in San Diego are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov