San Diego, CALIFORNIA33 Active Studies

Pulmonary Hypertension Clinical Trials in San Diego, CALIFORNIA

Find 33 actively recruiting pulmonary hypertension clinical trials in San Diego, CALIFORNIA. Connect with local research sites and explore new treatment options.

33
Active Trials
27
Sponsors
9,964
Enrolling

Recruiting Pulmonary Hypertension Studies in San Diego

RecruitingSan Diego, CALIFORNIANCT06191744

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

Follicular lymphoma (FL) is the second most common B-cell cancer and the most common type of cancer of lymphocytes. Unfortunately, this disease is incurable with conventional treatment and the disease...

1,095 participants
Genmab
View Study Details
RecruitingSan Diego, CALIFORNIANCT06289673

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

The goal of this study is to provide sufficient therapy during the time a patients' B-cell Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LLy) risk category is being determined. The ter...

850 participants
St. Jude Children's Research Hospital
View Study Details
RecruitingSan Diego, CALIFORNIANCT07114874

NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia

This study will evaluate the long-term safety of NBI-1117568 in adults with schizophrenia....

800 participants
Neurocrine Biosciences
View Study Details
RecruitingSan Diego, CALIFORNIANCT05100862

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

The purpose of the study is to compare the efficacy of zanubrutinib plus obinutuzumab versus lenalidomide plus rituximab (R\^2) in participants with relapsed/refractory (R/R) follicular lymphoma (FL),...

780 participants
BeiGene
View Study Details
RecruitingSan Diego, CALIFORNIANCT06943872

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

The goal of this study is to compare how well sonrotoclax plus obinutuzumab works versus venetoclax plus rituximab in treating adults with relapsed and/or refractory (R/R) chronic lymphocytic leukemia...

630 participants
BeiGene
View Study Details
RecruitingSan Diego, CALIFORNIANCT04557462

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

The purpose of this study is to evaluate the long-term safety and tolerability, of open label iptacopan in primary IgA nephropathy participants who have completed either the CLNP023X2203 or CLNP023A23...

540 participants
Novartis Pharmaceuticals
View Study Details
RecruitingSan Diego, CALIFORNIANCT06291376

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

The primary objective of this study to evaluate efficacy of ravulizumab compared with placebo on proteinuria reduction and change in eGFR in adult participants with IgAN who are at risk of disease pro...

510 participants
Alexion Pharmaceuticals, Inc.
View Study Details
RecruitingSan Diego, CALIFORNIANCT06229210

Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

This is a multicenter, global, 26-week, open-label study to assess the safety and tolerability of lumateperone in pediatric patients with schizophrenia, bipolar disorder or autism spectrum disorder....

500 participants
Intra-Cellular Therapies, Inc.
View Study Details
RecruitingSan Diego, CALIFORNIANCT05949593

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

This Phase 3, multicenter, double-masked, parallel-group, placebo-controlled, randomized, fixed-dose clinical study is designed to evaluate the efficacy and safety of tinlarebant (LBS-008) in subjects...

429 participants
Belite Bio, Inc
View Study Details
RecruitingSan Diego, CALIFORNIANCT05126277

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

This trial will evaluate efficacy, safety, and tolerability of subcutaneous (s.c.) ianalumab given every 4 weeks (q4w) or every 12 weeks (q12w) compared to placebo, in combination with SoC, in adult p...

420 participants
Novartis Pharmaceuticals
View Study Details
RecruitingSan Diego, CALIFORNIANCT06961968

Randomized Withdrawal Study in Patients With Schizophrenia

The purpose of this research is to evaluate the efficacy of dosing iloperidone long-acting injection (LAI) compared to placebo in preventing the exacerbation of symptoms in patients with schizophrenia...

400 participants
Vanda Pharmaceuticals
View Study Details
RecruitingSan Diego, CALIFORNIANCT06233799

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

The primary objective of this study is to evaluate the efficacy of extended release naltrexone plus bupropion XL (XR-NTX/BUP-XL) compared to matched injectable and oral placebo (iPLB/oPLB) in reducing...

360 participants
National Institute on Drug Abuse (NIDA)
View Study Details
RecruitingSan Diego, CALIFORNIANCT07038876

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Inpatient Adults With Schizophrenia

ML-007C-MA-211 is a Phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of orally administered ML-007C-MA in inpatient adult participants age...

300 participants
MapLight Therapeutics
View Study Details
RecruitingSan Diego, CALIFORNIANCT06963034

NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

The primary objective for this study is to evaluate the efficacy of NBI-1117568 compared with placebo on improving behavioral and psychological symptoms of schizophrenia in adults....

284 participants
Neurocrine Biosciences
View Study Details
RecruitingSan Diego, CALIFORNIANCT05826535

Study of LYL314 in Aggressive Large B-Cell Lymphoma

This is a Phase 1/2, multi-center, open-label study evaluating the safety and efficacy of LYL314, a dual-targeting chimeric antigen receptor (CAR) targeting cluster of differentiation (CD)19 and CD20 ...

270 participants
Lyell Immunopharma, Inc.
View Study Details
RecruitingSan Diego, CALIFORNIANCT06500273

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

This is a randomized, open-label study in adult patients who have completed standard first line therapy for large B-cell lymphoma (LBCL) and achieved a complete response or partial response suitable f...

250 participants
Allogene Therapeutics
View Study Details
RecruitingSan Diego, CALIFORNIANCT05382208

Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial)

The purpose of this study is to determine if doxycycline will reduce progression of emphysema in people living with HIV. The secondary objectives are to examine the effects of doxycycline on change i...

250 participants
Weill Medical College of Cornell University
View Study Details
RecruitingSan Diego, CALIFORNIANCT06777901

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

The goal of this clinical trial is to learn if the Auryon Atherectomy System with balloon angioplasty safe and effective in treating lower limb blockages. The main question it aims to answer is: Is tr...

224 participants
Angiodynamics, Inc.
View Study Details
RecruitingSan Diego, CALIFORNIANCT05561114

Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus

To evaluate the safety and efficacy of the ProTractX3â„¢ DCB for the treatment of benign esophageal strictures....

198 participants
GIE Medical
View Study Details
RecruitingSan Diego, CALIFORNIANCT06598462

A Study to Investigate the Efficacy and Safety of NSI-8226 in Adults With Eosinophilic Esophagitis

Phase 2 study to evaluate the safety, tolerability, PK, immunogenicity, and pharmacodynamics of solrikitug in adult participants with eosinophilic esophagitis....

157 participants
Uniquity One (UNI)
View Study Details
RecruitingSan Diego, CALIFORNIANCT06797869

A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy

This study will look at the effects of CagriSema in people with both type 2 diabetes and painful diabetic peripheral neuropathy, compared to placebo. Participants will either get an active medicine or...

134 participants
Novo Nordisk A/S
View Study Details
RecruitingSan Diego, CALIFORNIANCT05848687

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

The purpose of this study is to improve upon the TINI study treatment. The study will test the ability of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets...

90 participants
Tanja Andrea Gruber
View Study Details
RecruitingSan Diego, CALIFORNIANCT06470451

Confirmatory Study of Topical HyBryteâ„¢ vs. Placebo for the Treatment of CTCL

To evaluate the use of HyBryte, a topical photosensitizing agent, to treat patients with patch/plaque phase cutaneous T-cell lymphoma (mycosis fungoides)....

80 participants
Soligenix
View Study Details
RecruitingSan Diego, CALIFORNIANCT05465174

Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults

The current study assesses the tolerability and efficacy of monotherapy with pan-RAF-kinase (Tovorafenib) inhibition for the treatment of children and young adults with craniopharyngioma....

57 participants
Sabine Mueller, MD, PhD
View Study Details
RecruitingSan Diego, CALIFORNIANCT05345197

Emicizumab in Patients With Acquired Hemophilia A

This is a phase II multicenter open-label, single-arm prospective study to evaluate the efficacy of prophylactic emicizumab administered on a scheduled basis to prevent bleeds in patients with acquire...

51 participants
University of Washington
View Study Details
RecruitingSan Diego, CALIFORNIANCT06064097

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

This phase II trial tests effects of nivolumab in combination with chemotherapy drugs prior to radiation therapy patients with nasopharyngeal carcinoma (NPC). Immunotherapy with monoclonal antibodies,...

50 participants
National Cancer Institute (NCI)
View Study Details
RecruitingSan Diego, CALIFORNIANCT06534060

MB-105 in Patients With CD5 Positive T-cell Lymphoma

This is a single arm, two-stage, Phase 2, open-label, multicenter study of MB-105 in patients with CD5 Positive (CD5+) Relapsed / Refractory T-cell Lymphoma (r/r TCL). This study will apply a Simon tw...

46 participants
March Biosciences Inc
View Study Details
RecruitingSan Diego, CALIFORNIANCT05778188

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia

Hypoxic-ischemic encephalopathy (HIE) affects approximately 4,000 to 12,000 persons annually in the United States. Mortality from HIE has been reported up to 60%, with at least 25% of survivors left w...

42 participants
ReAlta Life Sciences, Inc.
View Study Details
RecruitingSan Diego, CALIFORNIANCT04450173

Obinutuzumab, Ibrutinib, and Venetoclax for the Treatment of Previously Untreated Stage II-IV Follicular Lymphoma

This phase II trial studies how well obinutuzumab, ibrutinib, and venetoclax work in treating patients with previously untreated stage II-IV follicular lymphoma. Immunotherapy with obinutuzumab may in...

40 participants
Joseph Tuscano
View Study Details
RecruitingSan Diego, CALIFORNIANCT06003387

Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

The purpose of this study is to assess the risk of bleeding due to failure of expected pharmacological action of CSL222 in adults with severe or moderately severe hemophilia B with detectable pretreat...

35 participants
CSL Behring
View Study Details
RecruitingSan Diego, CALIFORNIANCT03913559

Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia

This trial is a limited multi-center, Phase II study to evaluate inotuzumab ozogamicin (Besponsa) in pediatric patients with MRD positive CD22-positive B-lymphoblastic leukemia (B-ALL). Some patients...

32 participants
St. Jude Children's Research Hospital
View Study Details
RecruitingSan Diego, CALIFORNIANCT06910813

DFT383 in Pediatric Participants With Nephropathic Cystinosis

An open-label, multi-center, phase I/II study to assess the safety, tolerability and efficacy of DFT383 in pediatric participants with nephropathic cystinosis. The purpose of this clinical study is t...

30 participants
Novartis Pharmaceuticals
View Study Details
RecruitingSan Diego, CALIFORNIANCT07157787

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

The primary objective of this study is to evaluate the efficacy of ALXN1920 compared with placebo in participants with PMN who are at a high risk for disease progression using 24-hour urine protein cr...

30 participants
Alexion Pharmaceuticals, Inc.
View Study Details

About Pulmonary Hypertension Clinical Trials in San Diego

Pulmonary hypertension is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. It can lead to heart failure if untreated. Treatment includes vasodilators, endothelin receptor antagonists, and PDE-5 inhibitors.

There are currently 33 pulmonary hypertension clinical trials recruiting participants in San Diego, CALIFORNIA. These studies are seeking a combined 9,964 participants. Research is being sponsored by Genmab, St. Jude Children's Research Hospital, Neurocrine Biosciences and 24 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pulmonary Hypertension Clinical Trials in San Diego — FAQ

Are there pulmonary hypertension clinical trials in San Diego?

Yes, there are 33 pulmonary hypertension clinical trials currently recruiting in San Diego, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Diego?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you about next steps.

Are clinical trials in San Diego free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Diego studies also compensate for your time and travel.

What pulmonary hypertension treatments are being tested?

The 33 active trials in San Diego are testing new therapies including novel drugs, biologics, and treatment approaches for pulmonary hypertension.

Data updated March 2, 2026 from ClinicalTrials.gov