San Diego, CALIFORNIA6 Active Studies

Schizophrenia Clinical Trials in San Diego, CALIFORNIA

Find 6 actively recruiting schizophrenia clinical trials in San Diego, CALIFORNIA. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
2,404
Enrolling

Recruiting Schizophrenia Studies in San Diego

RecruitingSan Diego, CALIFORNIANCT07114874

NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia

This study will evaluate the long-term safety of NBI-1117568 in adults with schizophrenia....

800 participants
Neurocrine Biosciences
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RecruitingSan Diego, CALIFORNIANCT06229210

Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

This is a multicenter, global, 26-week, open-label study to assess the safety and tolerability of lumateperone in pediatric patients with schizophrenia, bipolar disorder or autism spectrum disorder....

500 participants
Intra-Cellular Therapies, Inc.
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RecruitingSan Diego, CALIFORNIANCT06961968

Randomized Withdrawal Study in Patients With Schizophrenia

The purpose of this research is to evaluate the efficacy of dosing iloperidone long-acting injection (LAI) compared to placebo in preventing the exacerbation of symptoms in patients with schizophrenia...

400 participants
Vanda Pharmaceuticals
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RecruitingSan Diego, CALIFORNIANCT07038876

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Inpatient Adults With Schizophrenia

ML-007C-MA-211 is a Phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of orally administered ML-007C-MA in inpatient adult participants age...

300 participants
MapLight Therapeutics
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RecruitingSan Diego, CALIFORNIANCT06963034

NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

The primary objective for this study is to evaluate the efficacy of NBI-1117568 compared with placebo on improving behavioral and psychological symptoms of schizophrenia in adults....

284 participants
Neurocrine Biosciences
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RecruitingSan Diego, CALIFORNIANCT04411225

Effects of Cannabidiol (CBD) Versus Placebo as an Adjunct to Treatment in Early Psychosis

This is an outpatient, single center, between-group, double blind, placebo controlled design. Approximately 120 adolescents and adult patients will be randomized to either have their treatment augment...

120 participants
University of California, San Diego
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About Schizophrenia Clinical Trials in San Diego

Schizophrenia is a chronic brain disorder affecting approximately 2.8 million US adults, characterized by hallucinations, delusions, disorganized thinking, and cognitive difficulties. While current treatments rely primarily on first- and second-generation antipsychotics (risperidone, olanzapine, clozapine), many patients experience incomplete symptom relief or significant side effects. Clinical trials are testing novel mechanisms including muscarinic receptor agonists (like KarXT/xanomeline-trospium), trace amine-associated receptor 1 (TAAR1) agonists, glutamate modulators, and long-acting injectable formulations. Treatment-resistant schizophrenia remains a major focus area, with trials seeking patients who have not adequately responded to standard antipsychotic therapy.

There are currently 6 schizophrenia clinical trials recruiting participants in San Diego, CALIFORNIA. These studies are seeking a combined 2,404 participants. Research is being sponsored by Neurocrine Biosciences, Intra-Cellular Therapies, Inc., Vanda Pharmaceuticals and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Schizophrenia Clinical Trials in San Diego — FAQ

Are there schizophrenia clinical trials in San Diego?

Yes, there are 6 schizophrenia clinical trials currently recruiting in San Diego, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Diego?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Diego research site will contact you about next steps.

Are clinical trials in San Diego free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Diego studies also compensate for your time and travel.

What schizophrenia treatments are being tested?

The 6 active trials in San Diego are testing new therapies including novel drugs, biologics, and treatment approaches for schizophrenia.

Data updated March 2, 2026 from ClinicalTrials.gov