San Francisco, CALIFORNIA12 Active Studies

Geographic Atrophy Clinical Trials in San Francisco, CALIFORNIA

Find 12 actively recruiting geographic atrophy clinical trials in San Francisco, CALIFORNIA. Connect with local research sites and explore new treatment options.

12
Active Trials
11
Sponsors
4,205
Enrolling

Recruiting Geographic Atrophy Studies in San Francisco

RecruitingSan Francisco, CALIFORNIANCT06393374

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

This is a randomized, open-label study comparing the efficacy and safety of adjuvant sacituzumab tirumotecan (MK-2870) in combination with pembrolizumab compared to treatment of physician's choice (TP...

1,530 participants
Merck Sharp & Dohme LLC
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RecruitingSan Francisco, CALIFORNIANCT06841354

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Researchers want to know if sacituzumab tirumotecan given alone or with pembrolizumab can treat triple negative breast cancer (TNBC). The main goal of this study is to learn if people treated with sac...

1,000 participants
Merck Sharp & Dohme LLC
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RecruitingSan Francisco, CALIFORNIANCT06291376

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

The primary objective of this study to evaluate efficacy of ravulizumab compared with placebo on proteinuria reduction and change in eGFR in adult participants with IgAN who are at risk of disease pro...

510 participants
Alexion Pharmaceuticals, Inc.
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RecruitingSan Francisco, CALIFORNIANCT06564142

Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)

The purpose of this study is to evaluate the efficacy of povetacicept in adult participants compared with placebo in reducing proteinuria and preserving renal function....

480 participants
Alpine Immune Sciences Inc, A Subsidiary of Vertex
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RecruitingSan Francisco, CALIFORNIANCT06719141

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

This (DEEp OCEAN Study) is a double-blind, randomized, placebo-controlled, multicenter study to investigate the efficacy, safety, and tolerability of LP352 in the treatment of seizures in children and...

320 participants
Longboard Pharmaceuticals
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RecruitingSan Francisco, CALIFORNIANCT03971409

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

This phase II trial studies how well the combination of avelumab with liposomal doxorubicin with or without binimetinib, or the combination of avelumab with sacituzumab govitecan works in treating pat...

150 participants
Laura Huppert, MD, BA
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RecruitingSan Francisco, CALIFORNIANCT06388083

A Phase 2/3 Study to Evaluate the Efficacy and Safety of Tinlarebant in Subjects With Stargardt Disease

The goal of this clinical trial is to evaluate the safety, tolerability, and efficacy of tinlarebant in subjects with Stargardt Disease...

60 participants
Belite Bio, Inc
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RecruitingSan Francisco, CALIFORNIANCT06712407

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

The goal of this clinical trial is to assess the efficacy and safety of extended TARPEYO® (delayed-release budesonide capsules) treatment in adult patients with primary IgA nephropathy who have comple...

60 participants
Calliditas Therapeutics AB
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RecruitingSan Francisco, CALIFORNIANCT04434040

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

The purpose of this study is to determine if a combination of two drugs sacituzumab govitecan and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulatin...

40 participants
Dana-Farber Cancer Institute
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RecruitingSan Francisco, CALIFORNIANCT05831176

A Study to Learn How Well Dupilumab Works in Adult and Adolescent Participants With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis and the Side Effects it May Have

This study is researching an experimental drug called dupilumab. The study is focused on participants with active eosinophilic gastritis (EoG) with or without eosinophilic duodenitis (EoD). Participan...

22 participants
Regeneron Pharmaceuticals
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RecruitingSan Francisco, CALIFORNIANCT03266640

Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovi...

20 participants
New York Medical College
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RecruitingSan Francisco, CALIFORNIANCT06467344

Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)

This study is an open-label, single ascending dose clinical trial in participants who have ABCA4-related retinopathies. This is the first-in-human clinical trial in which ACDN-01 will be evaluated for...

13 participants
Ascidian Therapeutics, Inc
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About Geographic Atrophy Clinical Trials in San Francisco

Geographic atrophy is the advanced form of dry age-related macular degeneration, involving progressive loss of retinal cells. It leads to enlarging blind spots in central vision. Recently approved complement inhibitor therapies can slow progression.

There are currently 12 geographic atrophy clinical trials recruiting participants in San Francisco, CALIFORNIA. These studies are seeking a combined 4,205 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Alexion Pharmaceuticals, Inc., Alpine Immune Sciences Inc, A Subsidiary of Vertex and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Geographic Atrophy Clinical Trials in San Francisco — FAQ

Are there geographic atrophy clinical trials in San Francisco?

Yes, there are 12 geographic atrophy clinical trials currently recruiting in San Francisco, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What geographic atrophy treatments are being tested?

The 12 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for geographic atrophy.

Data updated March 2, 2026 from ClinicalTrials.gov