San Francisco, CALIFORNIA5 Active Studies

Heart Failure Clinical Trials in San Francisco, CALIFORNIA

Find 5 actively recruiting heart failure clinical trials in San Francisco, CALIFORNIA. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
547
Enrolling

Recruiting Heart Failure Studies in San Francisco

RecruitingSan Francisco, CALIFORNIANCT06979362

A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure. Participants will either get CDR132L or placebo (...

200 participants
Novo Nordisk A/S
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RecruitingSan Francisco, CALIFORNIANCT06616974

A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)

TX000045-003 is a double-blind, randomized, parallel group, placebo-controlled, proof- of-concept (POC) study, evaluating 2 dose regimens of TX000045 over the course of a 24-week treatment period (the...

180 participants
Tectonic Therapeutic
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RecruitingSan Francisco, CALIFORNIANCT05034432

The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

To investigate the effect of VTA ablation at the time of LVAD implant to see if it can reduce the incidence of VTA after surgery...

100 participants
University of Rochester
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RecruitingSan Francisco, CALIFORNIANCT04703842

Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction

It is believed that targeted SERCA2a enzyme replacement in HFrEF patients will correct defective intracellular Ca2+ hemostasis, resulting in improved cardiac contractile function and energetics which ...

57 participants
Sardocor Corp.
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RecruitingSan Francisco, CALIFORNIANCT03629340

Metformin for Pulmonary Hypertension HFpEF

The main objective of this study is to determine the clinical efficacy of metformin versus placebo and the therapeutic response with regards to functional capacity and hemodynamics in PH-HFpEF....

10 participants
University of California, San Francisco
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About Heart Failure Clinical Trials in San Francisco

Heart failure is a chronic condition where the heart cannot pump blood efficiently to meet the body's needs. It affects millions of people worldwide and can result from various heart conditions. Treatment includes medications, lifestyle changes, devices, and in severe cases, heart transplant.

There are currently 5 heart failure clinical trials recruiting participants in San Francisco, CALIFORNIA. These studies are seeking a combined 547 participants. Research is being sponsored by Novo Nordisk A/S, Tectonic Therapeutic, University of Rochester and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Failure Clinical Trials in San Francisco — FAQ

Are there heart failure clinical trials in San Francisco?

Yes, there are 5 heart failure clinical trials currently recruiting in San Francisco, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What heart failure treatments are being tested?

The 5 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for heart failure.

Data updated March 2, 2026 from ClinicalTrials.gov