San Francisco, CALIFORNIA7 Active Studies

Non-Small Cell Lung Cancer Clinical Trials in San Francisco, CALIFORNIA

Find 7 actively recruiting non-small cell lung cancer clinical trials in San Francisco, CALIFORNIA. Connect with local research sites and explore new treatment options.

7
Active Trials
5
Sponsors
3,063
Enrolling

Recruiting Non-Small Cell Lung Cancer Studies in San Francisco

RecruitingSan Francisco, CALIFORNIANCT06692738

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

The purpose of ARTEMIDE-Lung02 is to assess the efficacy and safety of rilvegostomig in combination with platinum-based chemotherapy for the first-line (1L) treatment of patients with metastatic squam...

880 participants
AstraZeneca
View Study Details
RecruitingSan Francisco, CALIFORNIANCT06623422

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

The goal of this study is to learn if people who receive intismeran autogene and pembrolizumab after surgery are cancer-free longer than people who receive placebo and pembrolizumab. Researchers want ...

680 participants
Merck Sharp & Dohme LLC
View Study Details
RecruitingSan Francisco, CALIFORNIANCT06305754

Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)

The purpose of this study is to evaluate sacituzumab tirumotecan versus pemetrexed in combination with carboplatin for the treatment of epidermal growth factor receptor (EGFR)-mutated advanced non-squ...

520 participants
Merck Sharp & Dohme LLC
View Study Details
RecruitingSan Francisco, CALIFORNIANCT04165070

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) with or without chemotherapy in combination with vibostolimab (MK-7684), boserolimab (MK-5890), MK-4830, MK-04...

450 participants
Merck Sharp & Dohme LLC
View Study Details
RecruitingSan Francisco, CALIFORNIANCT06497556

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to assess the safety and efficacy of divarasib compared to locally approved KRAS G12C inhibitors (sotorasib or adagrasib) in participants with KRAS G12C-positive (KRAS G12...

320 participants
Hoffmann-La Roche
View Study Details
RecruitingSan Francisco, CALIFORNIANCT04302025

A Study of Multiple Therapies in Biomarker-Selected Patients With Resectable Stages IB-III Non-Small Cell Lung Cancer

This trial will evaluate the efficacy and safety of various therapies in patients with Stage IB, IIA, IIB, IIIA, or selected IIIB resectable and untreated non-small cell lung cancer (NSCLC) tumors tha...

125 participants
Genentech, Inc.
View Study Details
RecruitingSan Francisco, CALIFORNIANCT06116682

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a ...

88 participants
SWOG Cancer Research Network
View Study Details

About Non-Small Cell Lung Cancer Clinical Trials in San Francisco

Non-small cell lung cancer (NSCLC) accounts for about 85% of all lung cancers. Subtypes include adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. Treatment has been transformed by targeted therapies and immunotherapy based on specific genetic markers.

There are currently 7 non-small cell lung cancer clinical trials recruiting participants in San Francisco, CALIFORNIA. These studies are seeking a combined 3,063 participants. Research is being sponsored by AstraZeneca, Merck Sharp & Dohme LLC, Hoffmann-La Roche and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Non-Small Cell Lung Cancer Clinical Trials in San Francisco — FAQ

Are there non-small cell lung cancer clinical trials in San Francisco?

Yes, there are 7 non-small cell lung cancer clinical trials currently recruiting in San Francisco, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What non-small cell lung cancer treatments are being tested?

The 7 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for non-small cell lung cancer.

Data updated March 2, 2026 from ClinicalTrials.gov