San Francisco, CALIFORNIA4 Active Studies

Triple Negative Breast Cancer Clinical Trials in San Francisco, CALIFORNIA

Find 4 actively recruiting triple negative breast cancer clinical trials in San Francisco, CALIFORNIA. Connect with local research sites and explore new treatment options.

4
Active Trials
3
Sponsors
2,720
Enrolling

Recruiting Triple Negative Breast Cancer Studies in San Francisco

RecruitingSan Francisco, CALIFORNIANCT06393374

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

This is a randomized, open-label study comparing the efficacy and safety of adjuvant sacituzumab tirumotecan (MK-2870) in combination with pembrolizumab compared to treatment of physician's choice (TP...

1,530 participants
Merck Sharp & Dohme LLC
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RecruitingSan Francisco, CALIFORNIANCT06841354

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Researchers want to know if sacituzumab tirumotecan given alone or with pembrolizumab can treat triple negative breast cancer (TNBC). The main goal of this study is to learn if people treated with sac...

1,000 participants
Merck Sharp & Dohme LLC
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RecruitingSan Francisco, CALIFORNIANCT03971409

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

This phase II trial studies how well the combination of avelumab with liposomal doxorubicin with or without binimetinib, or the combination of avelumab with sacituzumab govitecan works in treating pat...

150 participants
Laura Huppert, MD, BA
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RecruitingSan Francisco, CALIFORNIANCT04434040

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

The purpose of this study is to determine if a combination of two drugs sacituzumab govitecan and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulatin...

40 participants
Dana-Farber Cancer Institute
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About Triple Negative Breast Cancer Clinical Trials in San Francisco

Triple-negative breast cancer (TNBC) lacks estrogen receptors, progesterone receptors, and excess HER2 protein, limiting targeted treatment options. It accounts for about 10-15% of breast cancers and tends to be more aggressive. Active research focuses on immunotherapy and novel drug combinations.

There are currently 4 triple negative breast cancer clinical trials recruiting participants in San Francisco, CALIFORNIA. These studies are seeking a combined 2,720 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Laura Huppert, MD, BA, Dana-Farber Cancer Institute. Clinical trial participation is free and participants receive study-related medical care at no cost.

Triple Negative Breast Cancer Clinical Trials in San Francisco — FAQ

Are there triple negative breast cancer clinical trials in San Francisco?

Yes, there are 4 triple negative breast cancer clinical trials currently recruiting in San Francisco, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What triple negative breast cancer treatments are being tested?

The 4 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for triple negative breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov