Santa Ana, CA5 Active Studies

Rheumatoid Arthritis Clinical Trials in Santa Ana, CA

Find 5 actively recruiting rheumatoid arthritis clinical trials in Santa Ana, CA. Connect with local research sites and explore new treatment options.

5
Active Trials
4
Sponsors
1,573
Enrolling

Recruiting Rheumatoid Arthritis Studies in Santa Ana

RecruitingSanta Ana, CANCT05816382

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 narcolepsy, who were exposed to previously tested doses of TAK-861....

500 participants
Takeda
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RecruitingSanta Ana, CANCT06373731

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD)

The goal of this clinical trial is to evaluate the efficacy, safety and pharmacokinetics of elamipretide in subjects with dry age-related macular degeneration (AMD). The main questions it aims to answ...

360 participants
Stealth BioTherapeutics Inc.
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RecruitingSanta Ana, CANCT06795048

A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration

This study is a Phase IIIb/IV, multicenter, randomized, two-arm, open-label 100-week study to investigate the efficacy, safety, and durability of intravitreal 6-mg faricimab administered at up to 24-w...

274 participants
Hoffmann-La Roche
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RecruitingSanta Ana, CANCT04567303

Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration

This is a first in-human study to investigate the safety, tolerability and efficacy of zifibancimig administered through intravitreal (IVT) injections and via the Port Delivery (PD) implant in partici...

251 participants
Hoffmann-La Roche
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RecruitingSanta Ana, CANCT04853251

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

This study will assess corneal endothelial cells in participants with nAMD treated with PDS refilled every 24 weeks (Q24W)....

188 participants
Genentech, Inc.
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About Rheumatoid Arthritis Clinical Trials in Santa Ana

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 5 rheumatoid arthritis clinical trials recruiting participants in Santa Ana, CA. These studies are seeking a combined 1,573 participants. Research is being sponsored by Takeda, Stealth BioTherapeutics Inc., Hoffmann-La Roche and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Santa Ana — FAQ

Are there rheumatoid arthritis clinical trials in Santa Ana?

Yes, there are 5 rheumatoid arthritis clinical trials currently recruiting in Santa Ana, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Santa Ana?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Santa Ana research site will contact you about next steps.

Are clinical trials in Santa Ana free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Santa Ana studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 5 active trials in Santa Ana are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated March 2, 2026 from ClinicalTrials.gov