5 Rheumatoid Arthritis Clinical Trials in Santa Ana, CA (2026)

Q: How do I join a clinical trial in Santa Ana?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Santa Ana research site will contact you.

Recruiting Rheumatoid Arthritis Studies in Santa Ana

NCT05816382Recruiting

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 narcolepsy, who were exposed to previously tested doses of TAK-861....

Santa Ana, CAPHASE2500 participantsTakeda

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NCT07228390Recruiting

A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.

The purpose of this study is to learn about the safety and effects of the study medicine (called Ritlecitinib) for the possible treatment of hidradenitis suppurativa (HS). HS is a disease causing long...

Santa Ana, CAPHASE2240 participantsPfizer

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NCT04853251Recruiting

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

This study will assess corneal endothelial cells in participants with nAMD treated with PDS refilled every 24 weeks (Q24W)....

Santa Ana, CAPHASE4188 participantsGenentech, Inc.

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NCT07205887Recruiting

A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO

EYE-RES-104 is a randomized, dose-masked study of intravitreal EYE103 in participants with neovascular age-related macular degeneration (NVAMD) or macular edema following branch retinal vein occlusion...

Santa Ana, CAPHASE2160 participantsEyeBiotech Ltd.

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NCT06991114Recruiting

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

A Basket Trial of Refractory Rheumatoid Arthritis (RA), Sjögren's Disease (SjD), Idiopathic Inflammatory Myopathies (IIMs) and Systemic Sclerosis (SSc) subjects to evaluate the safety and efficacy of ...

Santa Ana, CAPHASE290 participantsArtiva Biotherapeutics, Inc.

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About Rheumatoid Arthritis Clinical Trials in Santa Ana

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 5 rheumatoid arthritis clinical trials recruiting participants in Santa Ana, CA. These studies are seeking a combined 1,178 participants. Research is being sponsored by Takeda, Pfizer, Genentech, Inc. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Santa Ana — FAQ

Are there rheumatoid arthritis clinical trials in Santa Ana?

Yes, there are 5 rheumatoid arthritis clinical trials currently recruiting in Santa Ana, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Santa Ana?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Santa Ana research site will contact you about next steps.

Are clinical trials in Santa Ana free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Santa Ana studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 5 active trials in Santa Ana are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated July 22, 2026 from ClinicalTrials.gov