Santa Barbara, CALIFORNIA6 Active Studies

Lung Cancer Clinical Trials in Santa Barbara, CALIFORNIA

Find 6 actively recruiting lung cancer clinical trials in Santa Barbara, CALIFORNIA. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
4,609
Enrolling

Recruiting Lung Cancer Studies in Santa Barbara

RecruitingSanta Barbara, CALIFORNIANCT05555732

Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

This study is designed to assess the efficacy and safety of datopotamab deruxtecan (Dato-DXd) in combination with pembrolizumab versus pembrolizumab in combination with pemetrexed and platinum chemoth...

1,170 participants
Daiichi Sankyo
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RecruitingSanta Barbara, CALIFORNIANCT05502237

Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer

The primary objective of this study is to compare the effect of zimberelimab (ZIM) and domvanalimab (DOM) in combination with chemotherapy relative to pembrolizumab (PEMBRO) in combination with chemot...

1,069 participants
Gilead Sciences
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RecruitingSanta Barbara, CALIFORNIANCT05920356

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

The primary objectives are to compare progression-free survival (PFS) and overall survival (OS) in participants who receive sotorasib with platinum doublet chemotherapy versus participants who receive...

750 participants
Amgen
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RecruitingSanta Barbara, CALIFORNIANCT05215340

Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations

This study is designed to assess the efficacy and safety of datopotamab deruxtecan (Dato-DXd) in combination with pembrolizumab versus pembrolizumab alone in participants with advanced or metastatic n...

740 participants
Daiichi Sankyo
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RecruitingSanta Barbara, CALIFORNIANCT06875310

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

This is a trial to evaluate the efficacy, safety, and tolerability of adagrasib plus pembrolizumab plus platinum-doublet chemotherapy versus placebo plus pembrolizumab plus platinum-doublet chemothera...

630 participants
Mirati Therapeutics Inc.
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RecruitingSanta Barbara, CALIFORNIANCT06773910

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

This is an open-label, randomized study of BMS-986489 (atigotatug + nivolumab fixed-dose combination) vs durvalumab in limited-stage (LS)-small-cell lung cancer (SCLC) participants. The main goals of...

250 participants
SCRI Development Innovations, LLC
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About Lung Cancer Clinical Trials in Santa Barbara

Lung cancer is the leading cause of cancer death worldwide, starting in the cells of the lungs. The two main types are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Treatments include surgery, chemotherapy, radiation, immunotherapy, and targeted drugs.

There are currently 6 lung cancer clinical trials recruiting participants in Santa Barbara, CALIFORNIA. These studies are seeking a combined 4,609 participants. Research is being sponsored by Daiichi Sankyo, Gilead Sciences, Amgen and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lung Cancer Clinical Trials in Santa Barbara — FAQ

Are there lung cancer clinical trials in Santa Barbara?

Yes, there are 6 lung cancer clinical trials currently recruiting in Santa Barbara, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Santa Barbara?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Santa Barbara research site will contact you about next steps.

Are clinical trials in Santa Barbara free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Santa Barbara studies also compensate for your time and travel.

What lung cancer treatments are being tested?

The 6 active trials in Santa Barbara are testing new therapies including novel drugs, biologics, and treatment approaches for lung cancer.

Data updated March 2, 2026 from ClinicalTrials.gov