Santa Monica, CALIFORNIA8 Active Studies

Breast Cancer Clinical Trials in Santa Monica, CALIFORNIA

Find 8 actively recruiting breast cancer clinical trials in Santa Monica, CALIFORNIA. Connect with local research sites and explore new treatment options.

8
Active Trials
8
Sponsors
2,325
Enrolling

Recruiting Breast Cancer Studies in Santa Monica

RecruitingSanta Monica, CALIFORNIANCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

This is a prospective, randomized, double-blinded, placebo-controlled, multi-center, Phase 3 study of GLSI-100 immunotherapy in HLA-A\*02 positive and HER2/neu positive subjects who are at high risk f...

750 participants
Greenwich LifeSciences, Inc.
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RecruitingSanta Monica, CALIFORNIANCT06797635

Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

Researchers are looking for new ways to treat triple-negative breast cancer (TNBC) and hormone receptor (HR) low positive/human epidermal growth factor receptor-2 (HER2) negative breast cancer. The ma...

372 participants
Merck Sharp & Dohme LLC
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RecruitingSanta Monica, CALIFORNIANCT04802759

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

This is a Phase Ib/II, open-label, multicenter, randomized umbrella study in participants with breast cancer. The study is designed with the flexibility to open new treatment arms as new treatments be...

316 participants
Hoffmann-La Roche
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RecruitingSanta Monica, CALIFORNIANCT04851613

Study to Evaluate Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients With Locally Advanced or Metastatic HR+/HER2- Breast Cancer

Study LAE205INT3101 is a Phase Ib/III study to evaluate the efficacy and safety of the combination therapy with afuresertib plus fulvestrant (afuresertib/placebo plus fulvestrant in Phase III) in pati...

256 participants
Laekna Limited
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RecruitingSanta Monica, CALIFORNIANCT05710328

Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial

This phase II trial tests how well an imaging procedure called fludeoxyglucose F-18 (FDG) positron emission tomography/computed tomography (PET/CT) works in predicting response to standard of care che...

235 participants
ECOG-ACRIN Cancer Research Group
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RecruitingSanta Monica, CALIFORNIANCT06157892

A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

This clinical trial is studying solid tumor cancers. A solid tumor is one that starts in part of your body like your lungs or liver instead of your blood. Once they've grown bigger in one spot or spre...

172 participants
Seagen, a wholly owned subsidiary of Pfizer
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RecruitingSanta Monica, CALIFORNIANCT06590857

Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.

Phase 1b/2 open-label trial of 225Ac-DOTATATE (RYZ101) in subjects with ER+, HER2-negative unresectable or metastatic breast cancer expressing SSTRs....

124 participants
RayzeBio, Inc.
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RecruitingSanta Monica, CALIFORNIANCT06449222

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

This study is a Phase II, multi-site, randomized, open-label clinical study to evaluate the safety, efficacy, and pharmacokinetics (PK) of BNT327 at two dose levels in combination with chemotherapeuti...

100 participants
BioNTech SE
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About Breast Cancer Clinical Trials in Santa Monica

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 8 breast cancer clinical trials recruiting participants in Santa Monica, CALIFORNIA. These studies are seeking a combined 2,325 participants. Research is being sponsored by Greenwich LifeSciences, Inc., Merck Sharp & Dohme LLC, Hoffmann-La Roche and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Santa Monica — FAQ

Are there breast cancer clinical trials in Santa Monica?

Yes, there are 8 breast cancer clinical trials currently recruiting in Santa Monica, CALIFORNIA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Santa Monica?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Santa Monica research site will contact you about next steps.

Are clinical trials in Santa Monica free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Santa Monica studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 8 active trials in Santa Monica are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov