Scottsdale, ARIZONA7 Active Studies

Macular Degeneration Clinical Trials in Scottsdale, ARIZONA

Find 7 actively recruiting macular degeneration clinical trials in Scottsdale, ARIZONA. Connect with local research sites and explore new treatment options.

7
Active Trials
6
Sponsors
2,429
Enrolling

Recruiting Macular Degeneration Studies in Scottsdale

RecruitingScottsdale, ARIZONANCT06556368

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants with Neovascular (Wet) Age-related Macular Degeneration (wAMD)...

675 participants
Kodiak Sciences Inc
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RecruitingScottsdale, ARIZONANCT05407636

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD is characterized by ...

660 participants
AbbVie
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RecruitingScottsdale, ARIZONANCT06864988

4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

A Phase 3, Randomized, Double-Masked, Active-Controlled Trial in Adults with Macular Neovascularization Secondary to Age-Related Macular Degeneration...

400 participants
4D Molecular Therapeutics
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RecruitingScottsdale, ARIZONANCT06856577

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration

This is a multi-center, randomized, double-masked, active-comparator-controlled, Phase 3 study in a broad participant population (treatment-naïve and treatment-experienced) with neovascular (wet) age-...

284 participants
Adverum Biotechnologies, Inc.
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RecruitingScottsdale, ARIZONANCT06722157

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

This study is open to people 50 years or older with an eye condition called geographic atrophy. The purpose of this study is to compare a medicine called BI 771716 with a medicine called pegcetacoplan...

180 participants
Boehringer Ingelheim
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RecruitingScottsdale, ARIZONANCT06769048

A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

This study is open to adults aged 50 years and older with geographic atrophy that was diagnosed by imaging of the retina. The purpose of this study is to find out whether a medicine called BI 1584862 ...

138 participants
Boehringer Ingelheim
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RecruitingScottsdale, ARIZONANCT06664502

A 2-part Study Consisting of a Multiple Ascending Dose Safety Study in Participants With Macular Edema Following Branch Retinal Vein Occlusion and a Dose-finding Safety and Preliminary Efficacy Study in Participants With Either Diabetic Macular Edema or Neovascular Age-related Macular Degeneration

EYE-TIE-201 is a 2-part study to investigate the safety and effectiveness of a new drug being developed called EYE201. All participants in the study will receive a total of 3 injections of EYE201 int...

92 participants
EyeBiotech Ltd.
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About Macular Degeneration Clinical Trials in Scottsdale

Age-related macular degeneration (AMD) is the leading cause of severe vision loss in Americans over 50, affecting over 11 million people. Wet (neovascular) AMD involves abnormal blood vessel growth under the retina, while dry AMD involves gradual thinning of the macula and accumulation of drusen deposits. Current treatment for wet AMD relies on anti-VEGF injections (ranibizumab, aflibercept, faricimab), with newer high-dose and extended-interval formulations reducing treatment burden. For geographic atrophy (advanced dry AMD), complement inhibitors like pegcetacoplan (Syfovre) represent the first approved treatments. Clinical trials are testing gene therapies, implantable drug delivery systems, stem cell therapies, and novel targets beyond VEGF for both wet and dry AMD.

There are currently 7 macular degeneration clinical trials recruiting participants in Scottsdale, ARIZONA. These studies are seeking a combined 2,429 participants. Research is being sponsored by Kodiak Sciences Inc, AbbVie, 4D Molecular Therapeutics and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Macular Degeneration Clinical Trials in Scottsdale — FAQ

Are there macular degeneration clinical trials in Scottsdale?

Yes, there are 7 macular degeneration clinical trials currently recruiting in Scottsdale, ARIZONA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Scottsdale?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Scottsdale research site will contact you about next steps.

Are clinical trials in Scottsdale free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Scottsdale studies also compensate for your time and travel.

What macular degeneration treatments are being tested?

The 7 active trials in Scottsdale are testing new therapies including novel drugs, biologics, and treatment approaches for macular degeneration.

Data updated March 2, 2026 from ClinicalTrials.gov