6 Macular Degeneration Clinical Trials in Scottsdale, AZ (2026)

Q: How do I join a clinical trial in Scottsdale?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Scottsdale research site will contact you.

Recruiting Macular Degeneration Studies in Scottsdale

NCT06541704Recruiting

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

This study is researching experimental (study) drugs called pozelimab and cemdisiran. The study is focused on participants who have Geographic Atrophy (GA) caused by Age-related Macular Degeneration (...

Scottsdale, AZPHASE3975 participantsRegeneron Pharmaceuticals

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NCT07440225Recruiting

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

Researchers are looking for new ways to treat neovascular age-related macular degeneration (NVAMD). Available standard (usual) treatments for NVAMD, such as aflibercept, may not work for every person...

Scottsdale, AZPHASE2960 participantsEyeBiotech Ltd.

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NCT07482176Recruiting

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

This is a multi-center, randomized, double-masked, active-comparator-controlled, Phase 3 study in a broad participant population (treatment-naïve and treatment-experienced) with neovascular (wet) age-...

Scottsdale, AZPHASE3534 participantsAdverum Biotechnologies, Inc.

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NCT07064759Recruiting

Single Intravitreal Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

A Phase 3, Randomized, Double-Masked, Active-Controlled Trial in Adults with Macular Neovascularization Secondary to Age-Related Macular Degeneration...

Scottsdale, AZPHASE3480 participants4D Molecular Therapeutics

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NCT07215390Recruiting

A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio

A Phase 2, Randomized, Placebo-controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL-3007 in Combination with Syfovre/Pegcetacopla...

Scottsdale, AZPHASE2240 participantsApellis Pharmaceuticals, Inc.

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NCT07205887Recruiting

A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO

EYE-RES-104 is a randomized, dose-masked study of intravitreal EYE103 in participants with neovascular age-related macular degeneration (NVAMD) or macular edema following branch retinal vein occlusion...

Scottsdale, AZPHASE2160 participantsEyeBiotech Ltd.

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About Macular Degeneration Clinical Trials in Scottsdale

Age-related macular degeneration (AMD) is the leading cause of severe vision loss in Americans over 50, affecting over 11 million people. Wet (neovascular) AMD involves abnormal blood vessel growth under the retina, while dry AMD involves gradual thinning of the macula and accumulation of drusen deposits. Current treatment for wet AMD relies on anti-VEGF injections (ranibizumab, aflibercept, faricimab), with newer high-dose and extended-interval formulations reducing treatment burden. For geographic atrophy (advanced dry AMD), complement inhibitors like pegcetacoplan (Syfovre) represent the first approved treatments. Clinical trials are testing gene therapies, implantable drug delivery systems, stem cell therapies, and novel targets beyond VEGF for both wet and dry AMD.

There are currently 6 macular degeneration clinical trials recruiting participants in Scottsdale, AZ. These studies are seeking a combined 3,349 participants. Research is being sponsored by Regeneron Pharmaceuticals, EyeBiotech Ltd., Adverum Biotechnologies, Inc. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Macular Degeneration Clinical Trials in Scottsdale — FAQ

Are there macular degeneration clinical trials in Scottsdale?

Yes, there are 6 macular degeneration clinical trials currently recruiting in Scottsdale, AZ. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Scottsdale?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Scottsdale research site will contact you about next steps.

Are clinical trials in Scottsdale free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Scottsdale studies also compensate for your time and travel.

What macular degeneration treatments are being tested?

The 6 active trials in Scottsdale are testing new therapies including novel drugs, biologics, and treatment approaches for macular degeneration.

Data updated October 15, 2026 from ClinicalTrials.gov