34 Interstitial Cystitis Clinical Trials in St Louis, MO (2026)

Q: How do I join a clinical trial in St Louis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you.

Recruiting Interstitial Cystitis Studies in St Louis

NCT04005976Recruiting

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenoty...

St Louis, MO5,000 participantsThe University of Texas Health Science Center, Houston

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NCT01522183Recruiting

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Post-marketing safety data on patients treated and untreated with eculizumab or ravulizumab....

St Louis, MO3,000 participantsAlexion Pharmaceuticals, Inc.

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NCT07194265Recruiting

A Clinical Trial Assessing the Safety and Effectiveness of the DurAVR® THV System

Prospective, randomized, controlled, multicenter, international study. Up to 1054 subjects with a severe native calcific aortic stenosis who are determined by the local Heart Team to have an indicati...

St Louis, MO1,650 participantsAnteris Technologies Ltd.

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NCT04629014Recruiting

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

This study proposes to quantify and describe the quality of life of children with intestinal failure, and to identify the medical and socio-economic factors that impact this quality of life, using dat...

St Louis, MO750 participantsBoston Children's Hospital

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NCT05104710Recruiting

Intermuscular Coherence as a Biomarker for ALS

The specific aims of this study are to: 1. Determine if a painless and quick measurement of muscle activity using surface electrodes can help with the diagnosis of ALS. Specifically, we ask if a meas...

St Louis, MO650 participantsUniversity of Chicago

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NCT05656261Recruiting

APOL1 Genetic Testing in African Americans

Recent breakthroughs in medical genetics have discovered that a portion of kidney failure affecting the Black community is mediated by coding variants in a gene called apolipoprotein L1 (APOL1) - and ...

St Louis, MO600 participantsSt. Louis University

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NCT01299168Recruiting

Diagnostic and Therapeutic Applications in Microarrays in Organ Transplantation

The current standard for biopsy-based diagnoses of dysfunction of kidney transplants is the Banff Classification which represents arbitrary international consensus. Recent data-driven approaches using...

St Louis, MO500 participantsUniversity of Alberta

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NCT05581004Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

This is a first-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and anti-tumor activity of enzelkitug when administered as a single agent and in combination with atezolizum...

St Louis, MOPHASE1450 participantsGenentech, Inc.

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NCT07296887Recruiting

CARE Tool Study Aim 3

This study is a multi-site randomized trial to study the implementation of the CARE Tool and evaluate the CARE Tool. The CARE Tool is a web-based tool that gives people information about cancer care c...

St Louis, MONA430 participantsWashington University School of Medicine

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NCT07115940Recruiting

Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well

SELECT LATE trial aims to evaluate if addition of endovascular thrombectomy to medical management in patients presenting with acute ischemic stroke and a proximal large vessel occlusion in the anterio...

St Louis, MONA408 participantsAmrou Sarraj

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NCT06545331Recruiting

Study of XB010 in Subjects With Solid Tumors

This is a FIH study is to evaluate the safety, tolerability, PK, immunogenicity, and preliminary antitumor activity of XB010 as a single agent and in combination with pembrolizumab in subjects with lo...

St Louis, MOPHASE1396 participantsExelixis

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NCT04157179Recruiting

Cerebral Oxygen Metabolism in Children

The purpose of this research study is to better understand how blood flow and metabolism change can influence brain development in the early decades of life. We will examine brain blood flow and meta...

St Louis, MONA350 participantsWashington University School of Medicine

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NCT07312734Recruiting

Study to Enable New Diagnostics for Pulmonary Microbes in People With CF

Sputum culture has been the best approach to detect harmful bacteria in the lungs of people with cystic fibrosis (CF). With the widespread use of new CF therapies (like Trikafta and Alyftrak), it is m...

St Louis, MO300 participantsChris Goss

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NCT05991440Recruiting

Examining Racial and Socioeconomic Differences in Chronic Low Back Pain

The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of ch...

St Louis, MO240 participantsWashington University School of Medicine

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NCT07205718Recruiting

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

TAK-188 is a new medicine that targets a protein called CCR8, which is found on the surface of certain cells (Tregs) inside tumors. These cells can weaken the body's ability to fight cancer. TAK-188 m...

St Louis, MOPHASE1223 participantsTakeda

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NCT05422911Recruiting

Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

The investigators have used national VHA data to demonstrate real-world efficacy of abiraterone and enzalutamide in Veterans with mCRPC. In the real-world that is the VHA, the investigators have succe...

St Louis, MOPHASE2192 participantsSun Pharmaceutical Industries Limited

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NCT07078383Recruiting

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

The Goal of this Clinical Study is to evaluate the safety and effectiveness of the Rapidlink device in the repair or replacement of the supra-aortic vessels during open surgical repair of aortic disea...

St Louis, MONA150 participantsVascutek Ltd.

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NCT07217782Recruiting

Pain in Juvenile Arthritis

Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disease in children. The main symptoms of JIA, which are often the primary focus of treatment, include joint swelling, stiffness, a...

St Louis, MONA140 participantsWashington University School of Medicine

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NCT05764720Recruiting

Stereotactic Adaptive Radiation Therapy of Borderline Resectable Pancreatic Cancer an Individualized Approach

This trial is a single-arm, prospective, multi-center clinical trial designed to demonstrate that stereotactic adaptive radiotherapy using an ablatively dosed (50Gy,5fx) for treatment of borderline-re...

St Louis, MONA134 participantsVarian, a Siemens Healthineers Company

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NCT06859801Recruiting

A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

The objective of this study is to evaluate real-world outcomes (e.g., pain, patient reported outcomes, skeletal related events, healthcare utilization, etc.) in patients treated with both percutaneous...

St Louis, MO120 participantsSociety of Interventional Oncology

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NCT06710756Recruiting

Lead-212 PSV359 Therapy for Patients With Solid Tumors

Phase I/IIa image-guided, alpha-particle therapy study of \[203Pb\]Pb-PSV359 and \[212Pb\]Pb-PSV359 in patients with solid tumors that are known to be Fibroblast Activation Protein (FAP)-positive....

St Louis, MOPHASE1112 participantsPerspective Therapeutics

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NCT04914507Recruiting

A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

Anterior vertebral body tethering (AVBT) is a novel, minimally invasive, growth modulation technique that was recently approved by the FDA under a Humanitarian Device Exemption (HDE). The goal of AVBT...

St Louis, MONA106 participantsPediatric Spine Foundation

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NCT07033897Recruiting

Adapting, Implementing and Evaluating the Effectiveness of HARP for People With Disabilities

The Home Hazard Removal Program (HARP) is an effective fall prevention intervention program which targets home hazard identification/removal. In this study the investigators will examine the effective...

St Louis, MONA80 participantsWashington University School of Medicine

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NCT06925542Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

This is a single-arm, open-label, multicenter, ascending dose Phase 1 study evaluating the safety and preliminary efficacy of CTX112 in adult subjects with refractory autoimmune diseases, including ac...

St Louis, MOPHASE180 participantsCRISPR Therapeutics

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NCT06994676Recruiting

A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

Study CBX-250-001 is a Phase 1, open-label, dose-escalation study of CBX-250 in participants with relapsed/refractory AML, HR-MDS, CMML, and CML. Participants aged ≥ 12 years are planned to be enrolle...

St Louis, MOPHASE172 participantsCrossbow Therapeutics, Inc.

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NCT05977036Recruiting

BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast Cancer

This is a prospective study to assess the impact of biomarker driven, early therapeutic switching and delayed imaging with the incorporation of DiviTum® serum TK1 activity ("DiviTum® TKa") in patients...

St Louis, MONA65 participantsWashington University School of Medicine

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NCT07313592Recruiting

Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients

This is a prospective specimen collection study evaluating the feasibility of using the ChromoSeq® assay for upfront classification in a real-time clinical setting of pediatric and young adult acute l...

St Louis, MO60 participantsWashington University School of Medicine

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NCT07446322Recruiting

FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

This is an open-label, randomized, multicenter Phase 2 study to assess the efficacy and safety of FOLFIRI + bevacizumab + pelareorep vs. FOLFIRI + bevacizumab in patients with RAS-mutated, MSS mCRC wh...

St Louis, MOPHASE260 participantsOncolytics Biotech

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NCT06648434Recruiting

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

The investigators hypothesize that MK2 inhibition may improve efficacy of mFOLFIRINOX chemotherapy for patients with pancreatic ductal adenocarcinoma (PDAC)....

St Louis, MOPHASE151 participantsWashington University School of Medicine

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NCT06503367Recruiting

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

The goal of this observational study is to understand how young children with LAMA2-related dystrophy move and change over time. We will also learn about how this condition impacts other body systems....

St Louis, MO44 participantsNationwide Children's Hospital

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NCT07137416Recruiting

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

This phase I trial tests the safety, side effects, and best dose of pidnarulex in combination with trastuzumab deruxtecan in treating patients with breast cancer and other solid tumors that express va...

St Louis, MOPHASE136 participantsNational Cancer Institute (NCI)

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NCT07126158Recruiting

Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma

Advanced pancreatic cancer patients receiving treatment of adaptive stereotactic body radiotherapy (SBRT) with concurrent and adjuvant defactinib plus avutometinib will have increased progression-free...

St Louis, MOPHASE236 participantsWashington University School of Medicine

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NCT07473102Recruiting

PET Imaging of MMP Activation in AAA: Clinical Component

A first-in-human evaluation of \[64Cu\]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoi...

St Louis, MOEARLY_PHASE128 participantsWashington University School of Medicine

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NCT03988283Recruiting

Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors

The purpose of this research study is to learn about the safety and feasibility of giving a personalized DNA vaccine to people with central nervous system tumors that have returned or have been resist...

St Louis, MOPHASE17 participantsWashington University School of Medicine

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About Interstitial Cystitis Clinical Trials in St Louis

Interstitial cystitis/bladder pain syndrome is a chronic condition causing bladder pressure, bladder pain, and sometimes pelvic pain. It primarily affects women and can significantly impact quality of life. Treatment includes dietary changes, bladder instillations, oral medications, and neuromodulation.

There are currently 34 interstitial cystitis clinical trials recruiting participants in St Louis, MO. These studies are seeking a combined 16,520 participants. Research is being sponsored by The University of Texas Health Science Center, Houston, Alexion Pharmaceuticals, Inc., Anteris Technologies Ltd. and 21 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Interstitial Cystitis Clinical Trials in St Louis — FAQ

Are there interstitial cystitis clinical trials in St Louis?

Yes, there are 34 interstitial cystitis clinical trials currently recruiting in St Louis, MO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in St Louis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.

Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.

What interstitial cystitis treatments are being tested?

The 34 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for interstitial cystitis.

Data updated July 17, 2026 from ClinicalTrials.gov