Toronto, ONTARIO7 Active Studies

Rheumatoid Arthritis Clinical Trials in Toronto, ONTARIO

Find 7 actively recruiting rheumatoid arthritis clinical trials in Toronto, ONTARIO. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
372
Enrolling

Recruiting Rheumatoid Arthritis Studies in Toronto

RecruitingToronto, ONTARIONCT03118986

RCT of Olanzapine for Control of CIV in Children Receiving Highly Emetogenic Chemotherapy

Chemotherapy-induced nausea and vomiting (CINV) are among the most bothersome symptoms during cancer treatment according to children and their parents. Most children receiving highly emetogenic chemot...

200 participants
The Hospital for Sick Children
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RecruitingToronto, ONTARIONCT06046222

Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis

This study will enroll male and female subjects who are 18 years of age or older with Eosinophilic Granulomatosis With Polyangiitis....

45 participants
NS Pharma, Inc.
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RecruitingToronto, ONTARIONCT05095727

A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease Type 1a (GSD1a)

The main goal of this trial is to evaluate the safety and tolerability of mRNA-3745 via intravenous (IV) administration in adult and pediatric participants with GSD1a....

45 participants
ModernaTX, Inc.
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RecruitingToronto, ONTARIONCT05317858

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

The purpose of this study is to evaluate the safety and efficacy of targeted blood brain barrier opening with Exablate Model 4000 Type 2.0/2.1 for the treatment of NSCLC brain metastases in patients w...

30 participants
InSightec
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RecruitingToronto, ONTARIONCT04747431

A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

PBFT02 is a gene therapy for frontotemporal dementia intended to deliver a functional copy of the GRN gene to the brain. This study will assess the safety, tolerability and efficacy of this treatment ...

25 participants
Passage Bio, Inc.
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RecruitingToronto, ONTARIONCT05984927

NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular Degeneration

This study will evaluate the safety, tolerability, and preliminary efficacy of NG101 AAV gene therapy administered by subretinal injections into a single selected eye as a single selected dose for pat...

18 participants
Neuracle Genetics, Inc
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RecruitingToronto, ONTARIONCT06064890

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

The goal of this clinical study is to learn about an investigational gene therapy product called AVB-101, which is designed to treat a disease called Frontotemporal Dementia with Progranulin Mutations...

9 participants
AviadoBio Ltd
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About Rheumatoid Arthritis Clinical Trials in Toronto

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting approximately 1.3 million Americans, where the immune system mistakenly attacks joint linings, causing painful swelling, bone erosion, and joint deformity. Early diagnosis and treatment are critical to prevent irreversible damage. Current standard treatments include methotrexate and other DMARDs, TNF inhibitors (etanercept, infliximab), IL-6 inhibitors (tocilizumab), T-cell costimulation modulators (abatacept), and JAK inhibitors (tofacitinib, baricitinib). Clinical trials are now exploring next-generation targeted therapies, dual-pathway inhibitors, and treatment strategies aimed at achieving sustained remission rather than just symptom control. Patients with inadequate response to conventional DMARDs or biologics are commonly eligible for enrollment.

There are currently 7 rheumatoid arthritis clinical trials recruiting participants in Toronto, ONTARIO. These studies are seeking a combined 372 participants. Research is being sponsored by The Hospital for Sick Children, NS Pharma, Inc., ModernaTX, Inc. and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Rheumatoid Arthritis Clinical Trials in Toronto — FAQ

Are there rheumatoid arthritis clinical trials in Toronto?

Yes, there are 7 rheumatoid arthritis clinical trials currently recruiting in Toronto, ONTARIO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Toronto?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Toronto research site will contact you about next steps.

Are clinical trials in Toronto free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Toronto studies also compensate for your time and travel.

What rheumatoid arthritis treatments are being tested?

The 7 active trials in Toronto are testing new therapies including novel drugs, biologics, and treatment approaches for rheumatoid arthritis.

Data updated March 2, 2026 from ClinicalTrials.gov