Washington D.c., DC13 Active Studies

Breast Cancer Clinical Trials in Washington D.c., DC

Find 13 actively recruiting breast cancer clinical trials in Washington D.c., DC. Connect with local research sites and explore new treatment options.

13
Active Trials
13
Sponsors
4,084
Enrolling

Recruiting Breast Cancer Studies in Washington D.c.

RecruitingWashington D.c., DCNCT05827081

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

The purpose of this open-label, multicenter, phase IIIb, single-arm study is to characterize the efficacy and safety of the combination of ribociclib and standard adjuvant endocrine therapy (ET) on in...

1,400 participants
Novartis Pharmaceuticals
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RecruitingWashington D.c., DCNCT05150691

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1303/BNT323 in subjects with advanced solid tumors that express HER2....

796 participants
DualityBio Inc.
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RecruitingWashington D.c., DCNCT06435429

A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

The efficacy and safety of zanidatamab in combination with physician's choice of chemotherapy compared with trastuzumab in combination with physician's choice of chemotherapy will be evaluated for the...

550 participants
Jazz Pharmaceuticals
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RecruitingWashington D.c., DCNCT06533826

TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd

The purpose of this study is to test the safety and effectiveness of the sequence of two investigational drugs (trastuzumab deruxtecan followed by datopotamab deruxtecan, or datopotamab deruxtecan fol...

357 participants
Ana C Garrido-Castro, MD
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RecruitingWashington D.c., DCNCT05710328

Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial

This phase II trial tests how well an imaging procedure called fludeoxyglucose F-18 (FDG) positron emission tomography/computed tomography (PET/CT) works in predicting response to standard of care che...

235 participants
ECOG-ACRIN Cancer Research Group
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RecruitingWashington D.c., DCNCT05894239

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

This study will evaluate the efficacy and safety of inavolisib in combination with Phesgo (pertuzumab, trastuzumab, and rHuPH20 injection for subcutaneous use) compared with placebo in combination wit...

230 participants
Hoffmann-La Roche
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RecruitingWashington D.c., DCNCT03971409

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

This phase II trial studies how well the combination of avelumab with liposomal doxorubicin with or without binimetinib, or the combination of avelumab with sacituzumab govitecan works in treating pat...

150 participants
Laura Huppert, MD, BA
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RecruitingWashington D.c., DCNCT05900986

LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer

The aim of this Phase 1b/2 study is to investigate the safety, efficacy, and pharmacokinetics (PK) of a single dose of LS301-IT, a novel fluorescence imaging agent developed by Integro Theranostics (I...

100 participants
Integro Theranostics
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RecruitingWashington D.c., DCNCT04841148

Avelumab or Hydroxychloroquine with or Without Palbociclib to Eliminate Dormant Breast Cancer

This clinical trial will assess the safety and early efficacy of Hydroxychloroquine or Avelumab, with or without Palbociclib, in early-stage ER+ breast cancer patients who are found to harbor dissemin...

96 participants
Abramson Cancer Center at Penn Medicine
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RecruitingWashington D.c., DCNCT05501704

ETHAN - ET for Male BC

This research study is looking to see how well male breast cancer responds to preoperative treatment with endocrine therapy and which endocrine therapy regimen is the most effective treatment for male...

60 participants
Jose Pablo Leone
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RecruitingWashington D.c., DCNCT05256745

RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer

This is a pilot study to evaluate the effects of azeliragon to decrease cardiac toxicity from chemotherapy and the safety of azelirgaon when given with chemotherapy. The Investigators hypothesize that...

48 participants
Georgetown University
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RecruitingWashington D.c., DCNCT04837209

Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer

This research study is looking to see whether the combination of Dostarlimab and Niraparib plus Radiation Therapy (RT) is safe and effective in participants with metastatic triple negative breast canc...

32 participants
Massachusetts General Hospital
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RecruitingWashington D.c., DCNCT05458674

Tucatinib+Trastuzumab+Eribulin in HER2+ MBC

The purpose of this study is to evaluate the safety and efficacy of the three-drug combination of tucatinib, trastuzumab, and eribulin in patients with de novo and recurrent unresectable metastatic HE...

30 participants
Criterium, Inc.
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About Breast Cancer Clinical Trials in Washington D.c.

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 13 breast cancer clinical trials recruiting participants in Washington D.c., DC. These studies are seeking a combined 4,084 participants. Research is being sponsored by Novartis Pharmaceuticals, DualityBio Inc., Jazz Pharmaceuticals and 10 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in Washington D.c. — FAQ

Are there breast cancer clinical trials in Washington D.c.?

Yes, there are 13 breast cancer clinical trials currently recruiting in Washington D.c., DC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Washington D.c.?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Washington D.c. research site will contact you about next steps.

Are clinical trials in Washington D.c. free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Washington D.c. studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 13 active trials in Washington D.c. are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov