Orange, CANCT04031677Now EnrollingIRB Ready

Retroperitoneal Sarcoma Clinical Trial in Orange, CA

Access cutting-edge retroperitoneal sarcoma treatment through this clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by European Organisation for Research and Treatment of Cancer - EORTC

Quick Self-Assessment

See if you qualify for this Orange location

Preparing your pre-screening questions...

Expert Care in Orange

Access retroperitoneal sarcoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related retroperitoneal sarcoma treatment provided free

Apply for This Orange Location

Check if you qualify for this retroperitoneal sarcoma clinical trial in Orange, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Retroperitoneal Sarcoma Study in Orange

This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. After confirmation of eligibility criteria, patients will be randomized to either the standard arm or experimental arm.

Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Who Can Participate

Inclusion Criteria

Histologically proven primary high risk leiomyosarcoma (LMS) or Liposarcoma (LPS) of retroperitoneal space or infra-peritoneal spaces of pelvis.
Any grade LMS can be included
Minimum size of LMS tumor should be 5 cm
Diagnosis should be confirmed based on MDM2 (Mouse double minute 2 homolog) and CDK4 (Cyclin-dependent kinase 4) expression on IHC (immunohistochemistry), while proof of MDM2 amplification is highly recommended.
All grade 3 DDLPS can be included.
DDLPS with confirmed grade 2 on biopsy can be included when:
The grade 2 DDLPS has an FNCLCC score=5 (Fédération Nationale des Centres de Lutte Contre Le Cancer), and clear necrosis on imaging (whether or not present on the biopsy).
The tumors carry a high risk gene profile as determined by the Complexity INdex in SARComas (CINSARC-high)
Unifocal tumour
Resectable tumour: resectability is based on pre-o

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT04031677) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Retroperitoneal Sarcoma Treatment Options in Orange, CA

If you're searching for retroperitoneal sarcoma treatment options in Orange, CA, this clinical trial (NCT04031677) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this clinical trial. You'll receive care from experienced retroperitoneal sarcoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all retroperitoneal sarcoma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Orange, CA