Philadelphia, PANCT04889716Now EnrollingIRB Ready

Based on the study title "CAR-T Followed by Bispecific Antibodies" and the context of CAR-T therapy, this appears to be treating: Blood Cancer Clinical Trial in Philadelphia, PA

Access cutting-edge based on the study title "car-t followed by bispecific antibodies" and the context of car-t therapy, this appears to be treating: blood cancer treatment through this clinical trial at a research site in Philadelphia. Study-provided care at no cost to qualified participants.

Sponsored by Abramson Cancer Center at Penn Medicine

Quick Self-Assessment

See if you qualify for this Philadelphia location

Preparing your pre-screening questions...

Expert Care in Philadelphia

Access based on the study title "car-t followed by bispecific antibodies" and the context of car-t therapy, this appears to be treating: blood cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related based on the study title "car-t followed by bispecific antibodies" and the context of car-t therapy, this appears to be treating: blood cancer treatment provided free

Apply for This Philadelphia Location

Check if you qualify for this based on the study title "car-t followed by bispecific antibodies" and the context of car-t therapy, this appears to be treating: blood cancer clinical trial in Philadelphia, PA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Philadelphia

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Philadelphia site if eligible
  4. 4Begin participation

About This Based on the study title "CAR-T Followed by Bispecific Antibodies" and the context of CAR-T therapy, this appears to be treating: Blood Cancer Study in Philadelphia

The research study is being conducted to test the safety and effectiveness of the experimental drug mosunetuzumab (Cohort 1) or obinutuzumab and glofitamab (Cohort 2) when given after CAR (genetically modified) T cells. The study is for patients who have already received a CAR T-cell infusion. Some patients who join the study will receive mosunetuzumab, other patients later in the study may receive a different experimental drug (glofitamab, in combination with obinutuzumab).

Sponsor: Abramson Cancer Center at Penn Medicine

Who Can Participate

Inclusion Criteria

Life expectancy of at least 12 weeks
History of relapsed or refractory large B-cell lymphoma (including transformed follicular lymphoma, and follicular lymphoma Grade 3B) who have relapsed after or failed to respond to at least one prior standard systemic treatment regimen that contains an anthracycline and at least one containing an anti-CD20-directed therapy and for whom there is no available therapy expected to improve survival (e.g., standard chemotherapy, autologous or allogeneic stem cell transplant).
PET/CT scan (preferred), diagnostic CT scan, or MRI prior to CAR-T cell therapy, with at least one bi-dimensionally measurable lesion (≥ 1.5 cm for nodal lesion or ≥ 1cm for extra-nodal lesions in largest dimension by low-dose computerized tomography \[CT\] scan with FDG-uptake ≥ liver); this imaging must have been obtained within 56 days of receiving CAR T cell therapy.
PET/CT scan (preferred), diagnostic CT scan, or MRI with at least one bi-dimensional

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Philadelphia?

Yes, this clinical trial (NCT04889716) has an active research site in Philadelphia, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Based on the study title "CAR-T Followed by Bispecific Antibodies" and the context of CAR-T therapy, this appears to be treating: Blood Cancer Treatment Options in Philadelphia, PA

If you're searching for based on the study title "car-t followed by bispecific antibodies" and the context of car-t therapy, this appears to be treating: blood cancer treatment options in Philadelphia, PA, this clinical trial (NCT04889716) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Philadelphia research site is actively enrolling participants for this clinical trial. You'll receive care from experienced based on the study title "car-t followed by bispecific antibodies" and the context of car-t therapy, this appears to be treating: blood cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all based on the study title "car-t followed by bispecific antibodies" and the context of car-t therapy, this appears to be treating: blood cancer clinical trials near you to find additional studies recruiting in your area.

Ready to Join in Philadelphia?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Philadelphia, PA