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Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease

(NOSE-PD)

Sponsored by Gateway Institute for Brain Research

Quick Self-Assessment

See if you qualify and express your interest

Preparing your pre-screening questions...

Current Status

Recruiting

Auto-verified from ClinicalTrials.gov

Verified Apr 30, 2025

Phase

Clinical Trial

Sponsor

Gateway Institute for Brain Research

Enrollment Target

56

Start Date

Feb 2022

๐Ÿ“Š
1 of 56 participants interested
2% interest

Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

This study will be evaluating the safety and efficacy of insulin and glutathione in subjects with Parkinson's Disease compared to placebo.

Who Can Participate

Inclusion Criteria

Documented clinical diagnosis of idiopathic PD
Modified HY stage \< 5
Able to administer study drug or have a caregiver throughout the duration of the study to help administer drug
Willing to continue diet, exercise and medications reported at baseline consistently throughout participation in the trial. Essential changes are permitted
If taking PD medications or any nutraceuticals, must be on a stable dose for at least 30 days prior to Screening Visit. Essential changes will be permitted.
If subject is taking chronic antidepressant or an anxiolytic, must be on a stable dose for at least 90 days prior to Screening. Essential changes will be permitted. Key

Exclusion Criteria

Clinical diagnosis of Type 1 or Type 2 Diabetes Mellitus
Glycated hemoglobin (HbA1c) level โ‰ฅ 6.5%
History of hypoglycemia and/or documented plasma glucose levels of โ‰ค 50 mg/dL with or without symptoms of hypoglycemia
Mini-Mental State Exam (MMSE) score of โ‰ค 24 at Screen

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

๐Ÿ“‹

Study Type

INTERVENTIONAL

๐Ÿ‘ฅ

Target Enrollment

56 participants

๐ŸŽ‚

Age Range

30 Years - 85 Years

โšง

Gender

ALL

๐Ÿข

Sponsor

Gateway Institute for Brain Research

Study Locations

Choose your preferred location or select flexible during enrollment

RECRUITING

Davie

Florida

Location available
View Davie location page
RECRUITING

Hialeah

Florida

Location available
View Hialeah location page

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

Ready to Make a Difference?

Express your interest in this groundbreaking clinical trial

๐Ÿ”’ Secure ยท ๐Ÿฅ Expert Care

Find More Parkinsons Disease Trials by City

Browse all parkinsons disease clinical trials in these cities โ€” not just this study.

Looking for Parkinson's Disease Treatment in Davie?

Join others in Florida exploring innovative treatment options through clinical research

Parkinson's Disease Treatment Options in Davie, Florida

If you're searching for Parkinson's Disease treatment in Davie, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Davie, Hialeah and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Parkinson's Disease. All study-related care is provided at no cost to participants.

Local Sites
2 locations in Florida
Now Enrolling
Up to 56 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Parkinson's Disease?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Parkinson's Disease

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Parkinson's Disease Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT05266417. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.