Denver, CONCT05469893Now EnrollingIRB Ready

Smoldering Multiple Myeloma Clinical Trial in Denver, CO

Access cutting-edge smoldering multiple myeloma treatment through this clinical trial at a research site in Denver. Study-provided care at no cost to qualified participants.

Sponsored by Irene Ghobrial, MD

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Expert Care in Denver

Access smoldering multiple myeloma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related smoldering multiple myeloma treatment provided free

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Check if you qualify for this smoldering multiple myeloma clinical trial in Denver, CO

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Why Participate?

  • No-Cost Study Care

  • Local to Denver

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Denver site if eligible
  4. 4Begin participation

About This Smoldering Multiple Myeloma Study in Denver

The purpose of this study is to test the anti-cancer activity of Teclistamab and to compare it with Lenalidomide + Dexamethasone combination in people with high risk smoldering multiple myeloma. People with smoldering multiple myeloma (SMM) usually do not have symptoms but are at risk for progressing to active multiple myeloma (MM). Multiple Myeloma is a cancer of the plasma cells, which are an important part of the immune system. Patients with active multiple myeloma generally require treatmen

Sponsor: Irene Ghobrial, MD

Who Can Participate

Inclusion Criteria

Age ≥18 years.
1\) High risk SMM defined as having 1 of the following 2 criteria: High risk per "20-2-20" Criteria defined as presence of any two of the following: \-- Serum M spike ≥ 2 gm/dL, Involved to uninvolved free light chain (FLC) ratio≥ 20, Bone marrow Plasma Cell (BMPC) % ≥ 20%
OR total score of 9 using the following scoring system:
FLC Ratio \>10-25 = 2, \>25-40 = 3, \> 40 = 5
Serum M-Protein (g/dL) \>1.5-3 = 3, \>3 = 4
BMPC% \>15-20 = 2, \>20-30 = 3, \>30-40 = 5, \>40 = 6
Fluorescence In Situ Hybridization (FISH) abnormality (t(4,14), t(14,16), 1q gain, or del13q = 2
2\) Presence of ≥10% BMPC and at least one of the following: \-- Evolving pattern:
evolving Monoclonal Protein (eMP) (≥10% increase in Monoclonal Protein/Immunoglobulin (Ig)) within the first 6 months (only if M-protein ≥3 g/dl) and/or ≥25% increase in M/Ig within the first 12 months, with a minimum required increase of 0.5 g/dl in M-protein and/or 500 mg/dl

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Denver?

Yes, this clinical trial (NCT05469893) has an active research site in Denver, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Smoldering Multiple Myeloma Treatment Options in Denver, CO

If you're searching for smoldering multiple myeloma treatment options in Denver, CO, this clinical trial (NCT05469893) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Denver research site is actively enrolling participants for this clinical trial. You'll receive care from experienced smoldering multiple myeloma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all smoldering multiple myeloma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Denver, CO