Columbus, OHNCT05499013Now EnrollingIRB Ready

Polycythemia Vera Clinical Trial in Columbus, OH

Access cutting-edge polycythemia vera treatment through this clinical trial at a research site in Columbus. Study-provided care at no cost to qualified participants.

Sponsored by Silence Therapeutics plc

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Expert Care in Columbus

Access polycythemia vera specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related polycythemia vera treatment provided free

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Check if you qualify for this polycythemia vera clinical trial in Columbus, OH

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Why Participate?

  • No-Cost Study Care

  • Local to Columbus

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Columbus site if eligible
  4. 4Begin participation

About This Polycythemia Vera Study in Columbus

This is a Phase 1/2, multicenter study with an open-label dose escalation followed by a randomized placebo controlled and double-blind phase of SLN124 in adult patients with Polycythemia Vera (PV) to assess the safety, tolerability, efficacy, pharmacokinetic (PK), and Pharmacodynamic (PD) response of SLN124.

Sponsor: Silence Therapeutics plc

Who Can Participate

Inclusion Criteria

Male and female patients aged 18 years or older.
A confirmed diagnosis of PV according to the revised 2016 World Health Organization criteria:
Suitable phlebotomy history
Must agree to adhere to appropriate contraception requirements
Patients who are not receiving cytoreductive therapy must have been discontinued from any prior cytoreductive therapy for at least 24 weeks before dosing and have recovered from any adverse events due to cytoreductive therapy.
Patients receiving cytoreductive therapy with hydroxyurea, interferon, busulfan or ruxolitinib must have received a stable dose of cytoreductive therapy for at least 12 weeks before dosing and with no planned change in dose.
Patients must have had a dermatological examination within 6 months prior to screening.
Must have an Eastern Cooperative Oncology Group score of 0, 1, or 2.

Exclusion Criteria

Drug intolerance: 1. History of intolerance to oligonucleotides, or GalNAc, or any component

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Columbus?

Yes, this clinical trial (NCT05499013) has an active research site in Columbus, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Polycythemia Vera Treatment Options in Columbus, OH

If you're searching for polycythemia vera treatment options in Columbus, OH, this clinical trial (NCT05499013) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Columbus research site is actively enrolling participants for this clinical trial. You'll receive care from experienced polycythemia vera specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all polycythemia vera clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Columbus, OH