Durham, NCNCT05504291Now EnrollingIRB Ready

Retinoblastoma Clinical Trial in Durham, NC

Access cutting-edge retinoblastoma treatment through this clinical trial at a research site in Durham. Study-provided care at no cost to qualified participants.

Sponsored by Children's Oncology Group

Quick Self-Assessment

See if you qualify for this Durham location

Preparing your pre-screening questions...

Expert Care in Durham

Access retinoblastoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related retinoblastoma treatment provided free

Apply for This Durham Location

Check if you qualify for this retinoblastoma clinical trial in Durham, NC

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Durham

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Durham site if eligible
  4. 4Begin participation

About This Retinoblastoma Study in Durham

This phase II trial tests the safety and side effects of adding melphalan (by injecting it into the eye) to standard chemotherapy in early treatment of patients with retinoblastoma (RB). RB is a type of cancer that forms in the tissues of the retina (the light-sensitive layers of nerve tissue at the back of the eye). It may be hereditary or nonhereditary (sporadic). RB is considered harder to treat (higher risk) when there are vitreous seeds present. Vitreous seeds are RB tumors in the jelly-lik

Sponsor: Children's Oncology Group

Who Can Participate

Inclusion Criteria

Patient must be \< 18 years of age at enrollment
Patient must have newly diagnosed intraocular (localized) retinoblastoma and meet one of the following criteria:
Unilateral Group D retinoblastoma with vitreous seeding; OR
Bilateral retinoblastoma with worst eye Group D, with vitreous seeding present and the contralateral eye is Group A-C; OR
Bilateral Group D retinoblastoma with at least one eye with vitreous seeding; OR
Bilateral retinoblastoma with one Group D eye with vitreous seeding and one Group E eye where the Group E eye has been enucleated prior to any therapy. Note

Exclusion Criteria

for high-risk features
Bilateral retinoblastoma with one Group D eye with vitreous seeding and one Group E eye where the Group E eye has not been enucleated prior to any therapy at the discretion of the treating physician. Note exclusion for patients with evidence of metastatic or extra orbital spread
Patients must have a performance status corresponding to

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Durham?

Yes, this clinical trial (NCT05504291) has an active research site in Durham, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Retinoblastoma Treatment Options in Durham, NC

If you're searching for retinoblastoma treatment options in Durham, NC, this clinical trial (NCT05504291) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Durham research site is actively enrolling participants for this clinical trial. You'll receive care from experienced retinoblastoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all retinoblastoma clinical trials near you to find additional studies recruiting in your area.

More Essential Tremor Trials in Durham, NC

See all essential tremor clinical trials recruiting in Durham — not just this study.

Browse Essential Tremor Trials in Durham

Ready to Join in Durham?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Durham, NC