Los Angeles, CANCT05662228Now EnrollingIRB Ready

Down Syndrome Regression Disorder Clinical Trial in Los Angeles, CA

Access cutting-edge down syndrome regression disorder treatment through this clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by University of Colorado, Denver

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Expert Care in Los Angeles

Access down syndrome regression disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related down syndrome regression disorder treatment provided free

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Check if you qualify for this down syndrome regression disorder clinical trial in Los Angeles, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This Down Syndrome Regression Disorder Study in Los Angeles

Individuals with Down syndrome (DS) have an increased risk of numerous co-occurring conditions, including the neuropsychiatric condition known as Down Syndrome Regression Disorder (DSRD). A DSRD diagnosis often includes a sub-acute onset of catatonia, mutism, depersonalization, loss of ability to perform activities of daily living, hallucinations, delusions, and aggression and is most commonly observed in adolescents and young adults. The study evaluates the safety and efficacy of three current

Sponsor: University of Colorado, Denver

Who Can Participate

Inclusion Criteria

Individuals with DS between the ages of 8 and 30 years, inclusive. DS is broadly defined to include complete trisomy 21, Robertsonian translocation trisomy 21, partial trisomy 21 (segmental duplication), and mosaic trisomy 21.
Diagnosis of possible or probable DSRD per 2022 consensus guidelines.
Must agree to random treatment assignment.
Must agree to complete a washout of any medications intended to treat symptoms of DSRD or that may interfere with study interventions.
Must be able to present with a study partner or legal guardian at all study visits.

Exclusion Criteria

Weight less than 40 kg.
Pregnant or breast feeding.
Past or current tobacco smoking.
Poor venous access not allowing repeated blood tests or non-compliance with venipuncture requirements.
Known allergies, hypersensitivity, or intolerance to lorazepam, IVIG, or tofacitinib.
Participants may be excluded for other unforeseen reasons or confounding reasons for DSRD sym

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT05662228) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Down Syndrome Regression Disorder Treatment Options in Los Angeles, CA

If you're searching for down syndrome regression disorder treatment options in Los Angeles, CA, this clinical trial (NCT05662228) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this clinical trial. You'll receive care from experienced down syndrome regression disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all down syndrome regression disorder clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Los Angeles, CA