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NCT05687058RECRUITINGIRB Ready

Empagliflozin in ESKD - A Feasibility Study

Sponsored by University of Mississippi Medical Center

Quick Self-Assessment

See if you qualify and express your interest

Preparing your pre-screening questions...
📊
1 of 24 participants interested
4% interest

Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

The aim of this study is to learn about the safety of empagliflozin in dialysis patients as a preparation for a future large clinical trial. Empagliflozin has been approved by the Food and Drug Administration for the treatment of either type 2 diabetes, heart failure, or chronic kidney disease among patients not on dialysis. The use of empagliflozin has not been studied or approved among patients on dialysis for kidney failure because empagliflozin acts on the kidneys.

Who Can Participate

Inclusion Criteria

age ≥18 years; 2. diagnosis of end-stage kidney disease requiring dialysis, and 3. ability to provide informed consent.

Exclusion Criteria

systolic blood pressure \<100 mm Hg (pre-dialysis for HD patients) 2. two or more episodes of urinary tract infection within the last 12 months 3. history of urinary retention or urinary tract obstruction 4. liver cirrhosis 5. advanced heart failure requiring heart assist device or inotropic support 6. heart or liver transplant recipient 7. major surgery performed within the last 3 months ("major" per the investigator's assessment) 8. major surgery scheduled within 3 months after screening ("major" per the investigator's assessment) 9. active cancer 10. pregnant or lactating women 11. known allergy or hypersensitivity to any SGLT2 inhibitors 12. history of ketoacidosis during the last 12 months 13. any other medical condition considered unappropriated by their nephrologists or a study physician (i.e., cachexia, short li

❓ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

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Study Type

INTERVENTIONAL

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Target Enrollment

24 participants

Gender

ALL

🏢

Sponsor

University of Mississippi Medical Center

Study Locations

Choose your preferred location or select flexible during enrollment

RECRUITING

Jackson

Mississippi

Location available
RECRUITING

Jackson

Mississippi

Location available

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

Ready to Make a Difference?

Express your interest in this groundbreaking clinical trial

🔒 Secure · 🏥 Expert Care

Looking for End-stage kidney disease Treatment in Jackson?

Join others in Mississippi exploring innovative treatment options through clinical research

End-stage kidney disease Treatment Options in Jackson, Mississippi

If you're searching for End-stage kidney disease treatment in Jackson, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Jackson, Jackson and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with End-stage kidney disease. All study-related care is provided at no cost to participants.

Local Sites
2 locations in Mississippi
Now Enrolling
Up to 24 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for End-stage kidney disease?

Potential Benefits

  • Access to new treatment approaches before public availability
  • Close monitoring by experienced medical professionals
  • Study-related care provided at no cost
  • Contribute to medical research for End-stage kidney disease

What to Expect

  • Initial screening to determine eligibility
  • Regular check-ups and monitoring visits
  • Possible compensation for time and travel
  • You can withdraw at any time

Frequently Asked Questions About This End-stage kidney disease Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT05687058. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.