Philadelphia, PANCT06213649Now EnrollingIRB Ready

Acanthamoeba Keratitis Clinical Trial in Philadelphia, PA

Access cutting-edge acanthamoeba keratitis treatment through this clinical trial at a research site in Philadelphia. Study-provided care at no cost to qualified participants.

Sponsored by Jeremy Keenan, MD, MPH

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Expert Care in Philadelphia

Access acanthamoeba keratitis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related acanthamoeba keratitis treatment provided free

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Check if you qualify for this acanthamoeba keratitis clinical trial in Philadelphia, PA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Philadelphia

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Philadelphia site if eligible
  4. 4Begin participation

About This Acanthamoeba Keratitis Study in Philadelphia

The Parasitic Ulcer Treatment Trial (PUTT) is a multi-center, parallel-group, randomized clinical trial. The purpose of this study is to determine whether including topical corticosteroids in a regimen for acanthamoeba keratitis (AK) will improve vision. Patients presenting to all enrollment centers with evidence of acanthamoeba keratitis will be eligible for the trial if there is evidence of ocular inflammation after 4 weeks of anti-amoebic therapy. Those who agree to participate will be random

Sponsor: Jeremy Keenan, MD, MPH

Who Can Participate

Inclusion Criteria

AK on at least one of the following: culture, smear, PCR, shotgun sequencing, biopsy, or confocal microscopy
Ocular inflammation after 1 month of anti-amoebic treatment, defined as conjunctival, corneal, episcleral, or anterior chamber inflammation

Exclusion Criteria

Evidence or history of interstitial keratitis
Known herpetic keratitis, as determined from history, exam, or microbiological testing
Known fungal keratitis, as demonstrated from corneal scrapings
Corneal perforation or impending corneal perforation
Prior therapeutic keratoplasty for acanthamoeba keratitis
Unwillingness or inability to follow-up
No light perception in the affected eye
Known hypertensive response to steroids
Corticosteroid allergy
Concurrent treatment with systemic corticosteroids
Concurrent granulomatous amoebic encephalitis

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Philadelphia?

Yes, this clinical trial (NCT06213649) has an active research site in Philadelphia, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Acanthamoeba Keratitis Treatment Options in Philadelphia, PA

If you're searching for acanthamoeba keratitis treatment options in Philadelphia, PA, this clinical trial (NCT06213649) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Philadelphia research site is actively enrolling participants for this clinical trial. You'll receive care from experienced acanthamoeba keratitis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all acanthamoeba keratitis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Philadelphia, PA