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ZILRETTA in Subjects With Shoulder Osteoarthritis

Sponsored by Pacira Pharmaceuticals, Inc

Quick Self-Assessment

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Current Status

Recruiting

Auto-verified from ClinicalTrials.gov

Verified Nov 3, 2025

Phase

Clinical Trial

Sponsor

Pacira Pharmaceuticals, Inc

Enrollment Target

250

Start Date

Feb 2024

๐Ÿ“Š
1 of 250 participants interested
0% interest

Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

Primary Objective: To assess the efficacy of ZILRETTA on pain following an intra-articular (IA) injection in subjects with glenohumeral osteoarthritis (OA) relative to normal saline placebo Secondary Objective: * To assess the efficacy of ZILRETTA on pain following an IA injection in subjects with glenohumeral OA relative to triamcinolone acetonide injectable suspension, immediate release (TCA-IR) and normal saline placebo * To assess the safety of ZILRETTA in subjects with glenohumeral OA rel

Who Can Participate

Inclusion Criteria

Written informed consent has been obtained prior to initiating any study-specific procedures. 2. Willingness and ability to comply with the study procedures and visit schedules and ability to follow verbal and written instructions, including eDiary questionnaire completion requirements. 3. Subjects 50 to 80 years of age, inclusive, on the day of consent. 4. Body Mass Index (BMI) โ‰ค40 kg/m2. 5. Symptoms (including pain) associated with OA of the index shoulder for โ‰ฅ3 months prior to Screening Visit (subject self-report is acceptable). 6. Shoulder pain due to OA for \>15 days over the last month (as reported by the subject). 7. Grade 2 or 3 OA in the index glenohumeral joint based on the Samilson-Prieto classification system as confirmed by X-ray (axillary view and true anterior-posterior view) taken at, or within 6 months of, the Screening Visit and read by the central reader. 8. Average daily mean pain score โ‰ฅ4.0 and โ‰ค9.0 in index shoulder (0-10 numeric rating sc

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

๐Ÿ“‹

Study Type

INTERVENTIONAL

๐Ÿ‘ฅ

Target Enrollment

250 participants

๐ŸŽ‚

Age Range

50 Years - 80 Years

โšง

Gender

ALL

๐Ÿข

Sponsor

Pacira Pharmaceuticals, Inc

Study Locations

Choose your preferred location or select flexible during enrollment

RECRUITING

Vestavia Hills

Alabama

Location available
View Vestavia Hills location page
RECRUITING

Surprise

Arizona

Location available
View Surprise location page
RECRUITING

Tucson

Arizona

Location available
View Tucson location page
RECRUITING

La Mesa

California

Location available
View La Mesa location page
RECRUITING

Napa

California

Location available
View Napa location page
RECRUITING

Redwood City

California

Location available
View Redwood City location page
RECRUITING

Washington D.C.

District of Columbia

Location available
View Washington D.C. location page
COMPLETED

Atlantis

Florida

Location available
View Atlantis location page
RECRUITING

Maimi

Florida

Location available
View Maimi location page

๐Ÿ“ And 23 more locations available

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

Ready to Make a Difference?

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Looking for Shoulder Osteoarthritis Treatment in Vestavia Hills?

Join others in Alabama exploring innovative treatment options through clinical research

Shoulder Osteoarthritis Treatment Options in Vestavia Hills, Alabama

If you're searching for Shoulder Osteoarthritis treatment in Vestavia Hills, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Vestavia Hills, Surprise, Tucson and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Shoulder Osteoarthritis. All study-related care is provided at no cost to participants.

Local Sites
3 locations in Alabama
Now Enrolling
Up to 250 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Shoulder Osteoarthritis?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Shoulder Osteoarthritis

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Shoulder Osteoarthritis Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT06269705. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.