Eugene, ORNCT06465953Now EnrollingIRB Ready

Myelodysplastic Syndromes Clinical Trial in Eugene, OR

Access cutting-edge myelodysplastic syndromes treatment through this clinical trial at a research site in Eugene. Study-provided care at no cost to qualified participants.

Sponsored by Institut de Recherches Internationales Servier

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Expert Care in Eugene

Access myelodysplastic syndromes specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related myelodysplastic syndromes treatment provided free

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Check if you qualify for this myelodysplastic syndromes clinical trial in Eugene, OR

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Why Participate?

  • No-Cost Study Care

  • Local to Eugene

    Convenient for OR residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Eugene site if eligible
  4. 4Begin participation

About This Myelodysplastic Syndromes Study in Eugene

This study will enroll participants with myelodysplastic syndromes (MDS) with an Isocitrate dehydrogenase protein, 1 (IDH1) mutation, who have not received treatment with a hypomethylating agent previously. Participants will be randomized to receive either ivosidenib (IVO) alone or azacitidine (AZA) alone. IVO will be administered daily throughout the 28-day treatment cycle and AZA will be administered for the first 7 days of each 28-day cycle. Study visits will be conducted every week during Cy

Sponsor: Institut de Recherches Internationales Servier

Who Can Participate

Inclusion Criteria

Diagnosis of HMA naive IDH1 R132 mutated MDS defined according to WHO criteria (5th edition):
Moderate high, high and very high-risk MDS per IPSS-M score will be eligible regardless of blood counts and with blast counts 0-19%.
Low and moderate low-risk MDS per IPSS-M score must:
Have cytopenias related to MDS, defined as: \<100 platelets/microliter, or absolute neutrophil count (ANC) \<1000/mm3, or hemoglobin \<10g/dL AND
Have a blast count between 5-19% AND
Be eligible for HMA therapy (very low risk participants are to be excluded)
Locally or centrally confirmed IDH1 R132 C/G/H/L/S mutation

Exclusion Criteria

Received prior anticancer/disease modifying treatment for MDS (including HMA's, cytotoxic chemotherapy, investigational agents, bcl-2 inhibitor based-regimens, hematopoietic stem cell transplant (HSCT), IDH1 inhibitors). For LR-MDS patients, prior treatment with growth factors, luspatercept, lenalidomide, and imetelstat are allowed.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Eugene?

Yes, this clinical trial (NCT06465953) has an active research site in Eugene, OR that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Myelodysplastic Syndromes Treatment Options in Eugene, OR

If you're searching for myelodysplastic syndromes treatment options in Eugene, OR, this clinical trial (NCT06465953) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Eugene research site is actively enrolling participants for this clinical trial. You'll receive care from experienced myelodysplastic syndromes specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all myelodysplastic syndromes clinical trials near you to find additional studies recruiting in your area.

More Myelodysplastic Syndromes Trials in Eugene, OR

See all myelodysplastic syndromes clinical trials recruiting in Eugene — not just this study.

Browse Myelodysplastic Syndromes Trials in Eugene

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Secure · Expert Care · Eugene, OR