Chapel Hill, NCNCT06534060Now EnrollingIRB Ready

T-cell Lymphoma Clinical Trial in Chapel Hill, NC

Access cutting-edge t-cell lymphoma treatment through this clinical trial at a research site in Chapel Hill. Study-provided care at no cost to qualified participants.

Sponsored by March Biosciences Inc

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Expert Care in Chapel Hill

Access t-cell lymphoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related t-cell lymphoma treatment provided free

Apply for This Chapel Hill Location

Check if you qualify for this t-cell lymphoma clinical trial in Chapel Hill, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Chapel Hill

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chapel Hill site if eligible
  4. 4Begin participation

About This T-cell Lymphoma Study in Chapel Hill

This is a single arm, two-stage, Phase 2, open-label, multicenter study of MB-105 in patients with CD5 Positive (CD5+) Relapsed / Refractory T-cell Lymphoma (r/r TCL). This study will apply a Simon two-stage optimal design.

Sponsor: March Biosciences Inc

Who Can Participate

Inclusion Criteria

Male or female ≥ 18 years of age. 2. Patients with r/r TCL per WHO 2022 criteria. 1. r/r CTCL that has failed ≥ 2 prior lines of standard of care (SoC) therapy. 2. r/r PTCL that has failed ≥ 1 prior lines of SoC therapy. Note: patients with CD30+ disease should have received brentuximab vedotin. 3. Has available tumor tissue or is willing to undergo a biopsy procedure. 4. CD5 positivity confirmed by local laboratory using an approved diagnostic test or LDT. CD5 positivity is currently defined as having ≥ 50% CD5 expression. An exploratory cohort will enroll patients with CD5 expression below 50%. 5. Karnofsky performance score ≥ 70% or higher. 6. Prior CAR T-cell therapy must have occurred \> 60 days prior to study enrollment and must have no evidence of CAR persistence. 7. Measurable or detectable disease 1. PTCL per Lugano criteria 2. CTCL per Global (ISCL/EORTC/USCCL) criteria. 8. Prior autologous or allogenic hematopoietic stem cell transplant

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chapel Hill?

Yes, this clinical trial (NCT06534060) has an active research site in Chapel Hill, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

T-cell Lymphoma Treatment Options in Chapel Hill, NC

If you're searching for t-cell lymphoma treatment options in Chapel Hill, NC, this clinical trial (NCT06534060) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chapel Hill research site is actively enrolling participants for this clinical trial. You'll receive care from experienced t-cell lymphoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all t-cell lymphoma clinical trials near you to find additional studies recruiting in your area.

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