Boston, MANCT06561347Now EnrollingIRB Ready

Waldenstrom Macroglobulinemia Clinical Trial in Boston, MA

Access cutting-edge waldenstrom macroglobulinemia treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Massachusetts General Hospital

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Expert Care in Boston

Access waldenstrom macroglobulinemia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related waldenstrom macroglobulinemia treatment provided free

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Check if you qualify for this waldenstrom macroglobulinemia clinical trial in Boston, MA

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Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Waldenstrom Macroglobulinemia Study in Boston

The purpose of this study is to determine the very good partial response (VGPR) or better rate in participants with Waldenström macroglobulinemia (WM). The names of the study drugs involved in this study are as follows: zanubrutinib, bendamustine, and rituximab.

Sponsor: Massachusetts General Hospital

Who Can Participate

Inclusion Criteria

Clinicopathological diagnosis of waldenström macroglobulinemia (WM) per the second international workshop on waldenström macroglobulinemia (IWWM2) criteria
Presence of any MYD88 and CXCR4 mutation status, including MYD88 L265P mutation plus CXCR4 wild type, MYD88 L265P mutation plus CXCR4 mutation, or MYD88 wild type
Meeting criteria for treatment per IWWM2 criteria. At least one of the following:
Constitutional Symptoms (at least one of the following)
Recurrent fever
Night sweats
Weight loss
Progressive or symptomatic lymphadenopathy or splenomegaly
Hemoglobin ≤ 10 g/dL
Platelet count ≤ 100 k/uL
Hyperviscosity syndrome
Symptomatic peripheral neuropathy
Systemic amyloidosis
Renal insufficiency
Symptomatic cryoglobulinemia or cold agglutinemia
Treatment naive; must have not received any prior systemic therapy for WM
Participants with suspected or symptomatic hyperviscosity (e.g. noseblee

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT06561347) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Waldenstrom Macroglobulinemia Treatment Options in Boston, MA

If you're searching for waldenstrom macroglobulinemia treatment options in Boston, MA, this clinical trial (NCT06561347) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced waldenstrom macroglobulinemia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all waldenstrom macroglobulinemia clinical trials near you to find additional studies recruiting in your area.

More Waldenstrom Macroglobulinemia Trials in Boston, MA

See all waldenstrom macroglobulinemia clinical trials recruiting in Boston — not just this study.

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