Jackson, MSNCT06679855Now EnrollingIRB Ready

Post-ligation Cardiac Syndrome Clinical Trial in Jackson, MS

Access cutting-edge post-ligation cardiac syndrome treatment through this clinical trial at a research site in Jackson. Study-provided care at no cost to qualified participants.

Sponsored by NICHD Neonatal Research Network

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Expert Care in Jackson

Access post-ligation cardiac syndrome specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related post-ligation cardiac syndrome treatment provided free

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Check if you qualify for this post-ligation cardiac syndrome clinical trial in Jackson, MS

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Jackson

    Convenient for MS residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Jackson site if eligible
  4. 4Begin participation

About This Post-ligation Cardiac Syndrome Study in Jackson

The goal of this Phase 3, randomized, masked clinical trial is to is to find out whether milrinone, when given to infants after PDA closure, will help the heart work better by supplying oxygen to the lungs and tissues. The main questions it aims to answer are: 1. to determine if milrinone decreases the risk of death or PLCS within 7 days of the procedure, compared to standard treatment; and 2. to determine the effects of milrinone on two-year survival and neurodevelopmental outcome.

Sponsor: NICHD Neonatal Research Network

Who Can Participate

Inclusion Criteria

Gestational age at birth ≤27 weeks (and 6 days) and postnatal age \< 3 months at intervention
Invasive or non-invasive positive pressure respiratory support (does not include low flow nasal cannula)
Hemodynamically significant PDA with minimum transductal diameter ≥1.0 mm within 2 days of intervention
Decision by clinical team to proceed with PDA closure via surgical ligation or percutaneous cardiac catheterization based on clinical and echocardiography features of hemodynamic significance.

Exclusion Criteria

Any major congenital malformation
Congenital heart disease (except small (≤1mm) muscular ventricular septal defects, or small/moderate (\<3mm) atrial septal defect)
Acute renal failure defined by urine output \< 0.5 mL/kg/hour OR rise of serum creatinine by 0.3 mg/dL within 48 hours OR rise of serum creatinine more than 40% above baseline serum creatinine within prior 72 hours.
Systemic administration of vasodilator/inodilator agents

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Jackson?

Yes, this clinical trial (NCT06679855) has an active research site in Jackson, MS that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Post-ligation Cardiac Syndrome Treatment Options in Jackson, MS

If you're searching for post-ligation cardiac syndrome treatment options in Jackson, MS, this clinical trial (NCT06679855) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Jackson research site is actively enrolling participants for this clinical trial. You'll receive care from experienced post-ligation cardiac syndrome specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all post-ligation cardiac syndrome clinical trials near you to find additional studies recruiting in your area.

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