Rochester, MNNCT06839235Now EnrollingIRB Ready

Primary Hyperoxaluria Clinical Trial in Rochester, MN

Access cutting-edge primary hyperoxaluria treatment through this clinical trial at a research site in Rochester. Study-provided care at no cost to qualified participants.

Sponsored by Arbor Biotechnologies

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Expert Care in Rochester

Access primary hyperoxaluria specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related primary hyperoxaluria treatment provided free

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Check if you qualify for this primary hyperoxaluria clinical trial in Rochester, MN

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Why Participate?

  • No-Cost Study Care

  • Local to Rochester

    Convenient for MN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Rochester site if eligible
  4. 4Begin participation

About This Primary Hyperoxaluria Study in Rochester

The goal of the redePHine study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ABO-101 in participants with primary hyperoxaluria type 1 (PH1). The trial will consist of 2 Study Periods. During the first Study Period, there will be 2 parts. In Part A, adult participants will be treated with a single ascending dose to identify a recommended dose. In Part B, pediatric participants will be treated with the recommended dose. Following the first Study Period, parti

Sponsor: Arbor Biotechnologies

Who Can Participate

Inclusion Criteria

for Parts A and B
Documentation of PH1 as determined by genetic analysis confirming pathogenic mutations in the alanine-glyoxylate aminotransferase (AGXT) gene (valid historical laboratory data will be reviewed and approved by the Sponsor)
Age at time of signing the informed consent/assent form:
Part A: ≥18 years to ≤64 years
Part B: ≥6 years to \<18 years
24-hour UOx ≥0.7 mmol/24 hours/1.73 m²
eGFR ≥30 mL/min/1.73m²
Weight ≤90 kg Key

Exclusion Criteria

for Parts A and B
Confirmed diagnosis of primary hyperoxaluria type 2 or type 3
History of a liver, kidney or combined liver/kidney transplant
Currently on dialysis
Participant has previously used (within past 24 months) or is currently receiving an approved or investigational urinary oxalate lowering RNA interference (RNAi) or siRNA therapy
Female participants who are pregnant or breastfeeding (or are planning either during the first 12 months)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Rochester?

Yes, this clinical trial (NCT06839235) has an active research site in Rochester, MN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Primary Hyperoxaluria Treatment Options in Rochester, MN

If you're searching for primary hyperoxaluria treatment options in Rochester, MN, this clinical trial (NCT06839235) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Rochester research site is actively enrolling participants for this clinical trial. You'll receive care from experienced primary hyperoxaluria specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all primary hyperoxaluria clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Rochester, MN