โšกYour ready-to-use recruitment solution: IRB-compliant, SEO-optimized website that automatically routes qualified patient leads to your clinical study (14-day free trial, then $44/mo)

53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee

Sponsored by OrthoTrophix, Inc

Quick Self-Assessment

See if you qualify and express your interest

Preparing your pre-screening questions...

Current Status

Active, Not Recruiting

Auto-verified from ClinicalTrials.gov

Verified Feb 17, 2026

Phase

Clinical Trial

Sponsor

OrthoTrophix, Inc

Enrollment Target

270

Start Date

May 2025

๐Ÿ“Š
1 of 270 participants interested
0% interest

Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

53-Week Study Evaluating the Safety and Efficacy of Intra-articular (IA) Injections of TPX-100 vs Placebo in Subjects with Mild to Severe Tibio-Femoral Osteoarthritis of the Knee

Who Can Participate

Inclusion Criteria

Volunteers will be included in the study only if they satisfy all the following criteria: 1. Able to read, understand, sign, and date the subject informed consent. 2. Have given written informed consent before any study-related activities are carried out and are able to understand the nature and purpose of the trial, including possible risks and adverse effects. 3. Adult males and females, 50 to 80 years of age (inclusive) at Screening. 4. Body weight less than 136 kgs (300 lbs) at Screening. 5. Except for OA, subject is medically healthy (in the opinion of the PI), as determined by prestudy medical history, and without clinically significant abnormalities including: 1. Clinically relevant findings on physical examination that would preclude trial compliance. 2. Heart rate \<40 BPM or \>100 BPM after 5 minutes rest in supine or semi-supine position. 3. Body temperature \<95.9ยฐF or \>99.8ยฐF. Note: The above assessments may be repeated, if abnormal values a

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

๐Ÿ“‹

Study Type

INTERVENTIONAL

๐Ÿ‘ฅ

Target Enrollment

270 participants

๐ŸŽ‚

Age Range

50 Years - 80 Years

โšง

Gender

ALL

๐Ÿข

Sponsor

OrthoTrophix, Inc

Study Locations

Choose your preferred location or select flexible during enrollment

Unknown

Scottsdale

Arizona

Location available
View Scottsdale location page
Unknown

Tucson

Arizona

Location available
View Tucson location page
Unknown

Carrolton

California

Location available
View Carrolton location page
Unknown

Covina

California

Location available
View Covina location page
Unknown

Encinitas

California

Location available
View Encinitas location page
Unknown

Huntington Beach

California

Location available
View Huntington Beach location page
Unknown

Riverside

California

Location available
View Riverside location page
Unknown

Tujunga

California

Location available
View Tujunga location page
Unknown

Whittier

California

Location available
View Whittier location page

๐Ÿ“ And 24 more locations available

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

Ready to Make a Difference?

Express your interest in this groundbreaking clinical trial

๐Ÿ”’ Secure ยท ๐Ÿฅ Expert Care

Find More Osteoarthritis Trials by City

Browse all osteoarthritis clinical trials in these cities โ€” not just this study.

Browse More Trials by Condition

Looking for Knee Osteoarthritis Treatment in Scottsdale?

Join others in Arizona exploring innovative treatment options through clinical research

Knee Osteoarthritis Treatment Options in Scottsdale, Arizona

If you're searching for Knee Osteoarthritis treatment in Scottsdale, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Scottsdale, Tucson, Carrolton and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Knee Osteoarthritis. All study-related care is provided at no cost to participants.

Local Sites
3 locations in Arizona
Now Enrolling
Up to 270 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Knee Osteoarthritis?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Knee Osteoarthritis

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Knee Osteoarthritis Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT06865079. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.