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NCT06873945RECRUITINGIRB Ready

A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata

(ALLEGRO-100)

Sponsored by Pfizer

Quick Self-Assessment

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Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

The purpose of the study is to learn about the safety and effects of the study medicine (called ritlecitinib) for the treatment of alopecia areata. Alopecia areata is a disease that causes hair loss on the scalp, face, and areas of the body. Ritlecitinib is approved in many countries at a dose of 50 mg (milligram) taken by mouth once a day for the treatment of patients 12 years and older with severe alopecia areata. This study will look at both the 50 mg dose and a 100 mg dose.

Who Can Participate

Inclusion Criteria

Age: 1. 18 years of age or older at screening. Adolescents (12 to \<18 years of age at screening) are also eligible for this study, but only if permitted by the local IRB/EC and local regulatory health authority (if applicable). Where these approvals have not been granted, only participants 18 years of age and older at screening will be enrolled. Disease Characteristics: 2. Must meet the following alopecia areata criteria at both Screening and Baseline: 1. Have a clinical diagnosis of alopecia areata with no other etiology of hair loss. 2. โ‰ฅ50% hair loss of the scalp, as measured by SALT, without evidence of terminal hair regrowth within the previous 6 months. 3. Current episode of hair loss โ‰ค10 years.

Exclusion Criteria

Medical Conditions: 1. Diseases or conditions other than alopecia areata which affect hair loss, including other types of alopecia, other scalp disease that may impact the alopecia areata assessment, or active systemic diseases t

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

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Study Type

INTERVENTIONAL

๐Ÿ‘ฅ

Target Enrollment

550 participants

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Gender

ALL

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Sponsor

Pfizer

Study Locations

Choose your preferred location or select flexible during enrollment

RECRUITING

Hot Springs

Arkansas

Location available
View Hot Springs location page
RECRUITING

Brea

California

Location available
View Brea location page
NOT_YET_RECRUITING

Encinitas

California

Location available
View Encinitas location page
RECRUITING

Huntington Beach

California

Location available
View Huntington Beach location page
RECRUITING

Santa Ana

California

Location available
View Santa Ana location page
RECRUITING

Fairfield

Connecticut

Location available
View Fairfield location page
RECRUITING

Fort Myers

Florida

Location available
View Fort Myers location page
RECRUITING

Fort Myers

Florida

Location available
View Fort Myers location page
RECRUITING

Jacksonville

Florida

Location available
View Jacksonville location page

๐Ÿ“ And 36 more locations available

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

Ready to Make a Difference?

Express your interest in this groundbreaking clinical trial

๐Ÿ”’ Secure ยท ๐Ÿฅ Expert Care

Looking for Alopecia Areata Treatment in Hot Springs?

Join others in Arkansas exploring innovative treatment options through clinical research

Alopecia Areata Treatment Options in Hot Springs, Arkansas

If you're searching for Alopecia Areata treatment in Hot Springs, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Hot Springs, Brea, Encinitas and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Alopecia Areata. All study-related care is provided at no cost to participants.

Local Sites
3 locations in Arkansas
Now Enrolling
Up to 550 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Alopecia Areata?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Alopecia Areata

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Alopecia Areata Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT06873945. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.