Irvine, CANCT06910761Now EnrollingIRB Ready

Leptomeningeal Disease Clinical Trial in Irvine, CA

Access cutting-edge leptomeningeal disease treatment through this clinical trial at a research site in Irvine. Study-provided care at no cost to qualified participants.

Sponsored by City of Hope Medical Center

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Expert Care in Irvine

Access leptomeningeal disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related leptomeningeal disease treatment provided free

Apply for This Irvine Location

Check if you qualify for this leptomeningeal disease clinical trial in Irvine, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Irvine

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Irvine site if eligible
  4. 4Begin participation

About This Leptomeningeal Disease Study in Irvine

This phase II trial tests how well craniospinal irradiation (CSI) using photon volumetric modulated arc radiotherapy (VMAT) works in treating patients with breast cancer or non-small cell lung cancer (NSCLC) that has spread from the original (primary) tumor to the cerebrospinal fluid and meninges (thin layers of tissue that cover and protect the brain and spinal cord) (leptomeningeal disease). Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shr

Sponsor: City of Hope Medical Center

Who Can Participate

Inclusion Criteria

Documented informed consent of the participant and/or legally authorized representative
Assent, when appropriate, will be obtained per institutional guidelines
Karnofsky performance status (KPS) ≥ 60
Ability to read and understand English or Spanish for questionnaires, or ability to complete questionnaires using certified interpreter
Histologically confirmed breast cancer or non-small cell lung cancer
Leptomeningeal disease established either radiographically and/or CSF cytology
Absolute neutrophil count (ANC) ≥ 1,000/mm\^3
Hemoglobin ≥ 8 g/dL
Platelet ≥ 100,000/mm\^3
Creatinine clearance of ≥ 60 mL/min per 24 hour urine test or the Cockcroft-Gault formula
Women of childbearing potential (WOCBP): negative urine or serum pregnancy test
If the urine test is positive or cannot be confirmed as negative, a serum pregnancy test will be required
Agreement by females and males of childbearing potential to use an effective method

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Irvine?

Yes, this clinical trial (NCT06910761) has an active research site in Irvine, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Leptomeningeal Disease Treatment Options in Irvine, CA

If you're searching for leptomeningeal disease treatment options in Irvine, CA, this clinical trial (NCT06910761) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Irvine research site is actively enrolling participants for this clinical trial. You'll receive care from experienced leptomeningeal disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all leptomeningeal disease clinical trials near you to find additional studies recruiting in your area.

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