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A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China

Sponsored by Alebund Pharmaceuticals

Quick Self-Assessment

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Current Status

Recruiting

Auto-verified from ClinicalTrials.gov

Verified Jan 29, 2026

Phase

Clinical Trial

Sponsor

Alebund Pharmaceuticals

Enrollment Target

264

Start Date

Jun 2025

๐Ÿ“Š
1 of 264 participants interested
0% interest

Express Your Interest Today

Interested in learning more? Complete the form below.

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Advance Medical Science

    Contribute to groundbreaking research

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel (varies by study)

  • Help Others

    Benefit future patients

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3In-person assessment if eligible
  4. 4Begin participation

About This Study

The goal of this clinical trial is to learn if AP301 could work in the patients receiving maintenance dialysis with elevated blood phosphate.

Who Can Participate

Inclusion Criteria

Provision of signed and dated ICF
Adult when signing the ICF
Patients on dialysis for โ‰ฅ 3 months before signing the ICF and throughout the study
For HD patients, spKt/V โ‰ฅ 1.2; for PD patients, total Kt/V โ‰ฅ 1.7/week
Patients who receive phosphate binders over 4 weeks and their serum phosphate level is: 1. Screening: 1.13 mmol/L (3.5 mg/dL) โ‰ค serum phosphate \< 2.58 mmol/L (8.0 mg/dL) 2. After washout: 1.94 mmol/L (6.0 mg/dL) โ‰ค serum phosphate \< 3.23 mmol/L (10.0 mg/dL) Key

Exclusion Criteria

History or plan of kidney transplantation
History or plan of parathyroid intervention 6 months before signing the ICF
Serum calcium \< 1.9 mmol/L (7.6 mg/dL) or \> 2.75 mmol/L (11 mg/dL) at screening
Serum intact parathyroid hormone \> 127 pmol/L (1200 pg/mL) at screening
Presence of clinically significant gastrointestinal (GI) disorder
History of gastrectomy or duodenectomy, or GI surgery within 3 months before signing the ICF
Known allergic

โ“ Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility during the screening process.

Study Details

๐Ÿ“‹

Study Type

INTERVENTIONAL

๐Ÿ‘ฅ

Target Enrollment

264 participants

โšง

Gender

ALL

๐Ÿข

Sponsor

Alebund Pharmaceuticals

Study Locations

Choose your preferred location or select flexible during enrollment

RECRUITING

Granada Hills

California

Location available
View Granada Hills location page
RECRUITING

San Dimas

California

Location available
View San Dimas location page
RECRUITING

San Dimas

California

Location available
View San Dimas location page
RECRUITING

Lone Tree

Colorado

Location available
View Lone Tree location page
RECRUITING

Orange

Connecticut

Location available
View Orange location page
RECRUITING

Fort Myers

Florida

Location available
View Fort Myers location page
RECRUITING

Dalton

Georgia

Location available
View Dalton location page
RECRUITING

Baton Rouge

Louisiana

Location available
View Baton Rouge location page
RECRUITING

Columbus

Mississippi

Location available
View Columbus location page

๐Ÿ“ And 10 more locations available

Frequently Asked Questions

Q:What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Q:Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Q:Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Q:Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

Q:How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.

Still have questions? Our study coordinators are here to help.

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Looking for Hyperphosphatemia Treatment in Lone Tree?

Join others in Colorado exploring innovative treatment options through clinical research

Hyperphosphatemia Treatment Options in Lone Tree, Colorado

If you're searching for Hyperphosphatemia treatment in Lone Tree, participating in a clinical research study may provide access to innovative approaches under expert medical supervision. This study is actively recruiting participants in Lone Tree, Orange, Fort Myers and surrounding areas.

Clinical trials offer participants the opportunity to receive cutting-edge treatments while contributing to medical research that may help future patients with Hyperphosphatemia. All study-related care is provided at no cost to participants.

Local Sites
3 locations in Colorado
Now Enrolling
Up to 264 participants
Quick Start
Screening available now

Why Consider a Clinical Trial for Hyperphosphatemia?

Potential Benefits

  • โœ“Access to new treatment approaches before public availability
  • โœ“Close monitoring by experienced medical professionals
  • โœ“Study-related care provided at no cost
  • โœ“Contribute to medical research for Hyperphosphatemia

What to Expect

  • โ†’Initial screening to determine eligibility
  • โ†’Regular check-ups and monitoring visits
  • โ†’Possible compensation for time and travel
  • โ†’You can withdraw at any time

Frequently Asked Questions About This Hyperphosphatemia Study

Important Clinical Trial Information

This information is provided for educational purposes and does not constitute medical advice. Clinical trial participation involves potential risks and benefits. Eligibility requirements apply and will be assessed during the screening process.

Study identifier: NCT06933472. For complete study details, visit ClinicalTrials.gov. Always consult with your healthcare provider before making decisions about your medical care or participating in clinical research.