Pasadena, CANCT06999733Now EnrollingIRB Ready

Neurotrophic Keratitis Clinical Trial in Pasadena, CA

Access cutting-edge neurotrophic keratitis treatment through this clinical trial at a research site in Pasadena. Study-provided care at no cost to qualified participants.

Sponsored by Krystal Biotech, Inc.

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Expert Care in Pasadena

Access neurotrophic keratitis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related neurotrophic keratitis treatment provided free

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Check if you qualify for this neurotrophic keratitis clinical trial in Pasadena, CA

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Why Participate?

  • No-Cost Study Care

  • Local to Pasadena

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Pasadena site if eligible
  4. 4Begin participation

About This Neurotrophic Keratitis Study in Pasadena

The Sponsor is developing KB801, a replication-defective, non-integrating herpes simplex virus type 1 (HSV-1)-derived vector engineered to deliver functional full-length human nerve growth factor (NGF) to the corneas of people with Stage 2 or 3 neurotrophic keratitis (NK) via topical application. This is a Phase 1/2, multicenter, double-masked, placebo-controlled study to evaluate the safety, tolerability, and preliminary efficacy of KB801 in these subjects.

Sponsor: Krystal Biotech, Inc.

Who Can Participate

Inclusion Criteria

The subject must have read, understood, and signed an Institutional Review Board (IRB) approved Informed Consent Form and must be willing and able to comply with study procedures and instructions. 2. Aged ≥ 18 years at the time of informed consent. 3. Diagnosis of Stage 2 or Stage 3 NK, as defined by the Mackie criteria. 4. Persistent corneal epithelial defect (PCED) of at least 2 weeks duration without clinical improvement during that time. PCED is defined as a focal loss of the cornea's outermost cell layer and can include involvement of the deeper stromal layers (i.e., corneal ulcer). 5. PCED at Screening 1 must have a minimum of 1 mm of any linear measurement of defect. 6. Decreased corneal sensitivity (≤ 4 cm using the Cochet-Bonnet esthesiometer \[CBE\]) within the area of the PCED and in at least one corneal quadrant outside of the area of the defect. 7. A negative pregnancy test at Screening 1 and Day 1 for women of child-bearing potential.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Pasadena?

Yes, this clinical trial (NCT06999733) has an active research site in Pasadena, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Neurotrophic Keratitis Treatment Options in Pasadena, CA

If you're searching for neurotrophic keratitis treatment options in Pasadena, CA, this clinical trial (NCT06999733) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Pasadena research site is actively enrolling participants for this clinical trial. You'll receive care from experienced neurotrophic keratitis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all neurotrophic keratitis clinical trials near you to find additional studies recruiting in your area.

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