NCT05064540 · Endologix
JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization
(JAGUAR)
What this study is about
forward-looking, randomly assigned, multi-center study designed to evaluate the outcomes of commercially available contemporary EVAR in a real-world population. Patients will be randomly assigned into two device cohorts and compared across the primary endpoints. Patients will be followed procedurally to discharge, at 1, 6, 12 months and annually through to 5 years (total follow-up commitment).
View original scientific description
Prospective, randomized, multi-center study designed to evaluate the outcomes of commercially available contemporary EVAR in a real-world population. Patients will be randomized into two device cohorts and compared across the primary endpoints. Patients will be followed procedurally to discharge, at 1, 6, 12 months and annually through to 5 years (total follow-up commitment).
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Adult age 21 and older
- Subjects with minimum of 2 year life expectancy
- Subjects have signed the informed consent document
- Subjects with unruptured infrarenal AAA who are assessed by the Investigator to be eligible for endovascular Abdominal Aortic Aneurysm Repair with the trial devices.
- Patient must be able and willing to comply with all required follow-up exams.
Exclusion criteria
- Currently participating in another trial where the primary endpoint has not been reached yet.
- Known allergy to any of the device components
- Pregnant (females of childbearing potential only)
- Known connective tissue disorders
- Known active infection
- Subjects with pre-existing EVAR, i.e., in need of repair/intervention of a previously failed EVAR.
- Patient has other medical, social, or psychological conditions that, in the opinion of the investigator, preclude them from receiving the pre-treatment, required treatment, and post-treatment procedures and evaluations.
Where
- Huntsville, Alabama
- Tucson, Arizona
- Fayetteville, Arkansas
- Little Rock, Arkansas
- La Jolla, California
- San Diego, California
- Washington D.C., District of Columbia
- Jacksonville, Florida
- Lakeland, Florida
- Miami, Florida
- Iowa City, Iowa
- Louisville, Kentucky
And 16 more locations — see the full list below.
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jun 8, 2025 · Source of record for eligibility and locations