Dayton, OHNCT06778434Now EnrollingIRB Ready

Actinic Keratosis Clinical Trial in Dayton, OH

Access cutting-edge actinic keratosis treatment through this clinical trial at a research site in Dayton. Study-provided care at no cost to qualified participants.

Sponsored by VA Office of Research and Development

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Expert Care in Dayton

Access actinic keratosis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related actinic keratosis treatment provided free

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Check if you qualify for this actinic keratosis clinical trial in Dayton, OH

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Dayton

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Dayton site if eligible
  4. 4Begin participation

About This Actinic Keratosis Study in Dayton

The purpose of this study is to test the use of topical imipramine in combination with topical photodynamic therapy's (PDT) effect on the effectiveness and pain immunosuppression following treatment. PDT is a commonly used treatment in dermatology for patients who have many pre-cancers (actinic keratosis or "AK") on their skin. These are both FDA-approved medications, but this study is evaluating their use in combination, which has not been evaluated in the past. The investigators have been doing studies using mice that suggest imipramine might reduce immune system suppression by PDT thus allowing it to work better. Subjects whose provider has decided that they may benefit from PDT to treat their skin due to many AK precancerous lesions will be recruited for this study. Please note that the PDT itself is not experimental, only the imipramine treatment to the skin. There is a separate informed consent for the PDT.

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

Adult Males and Females ages 18 and older who are patients at the Dayton VAMC Dermatology clinics
Skin type must be "Fair", Fitzpatrick type I or II, due to the presence of actinic damage in this population.
Subjects must have a VA physician's order to receive PDT treatment on their forearms.
Willing to participate and understand the informed consent document.
Willing to avoid excess sun exposure/tanning beds to the area to be treated with PDT.
Has stable transportation to attend study visits at DVA

Exclusion Criteria

Currently taking any tricyclic antidepressants (TCAs)
Currently taking any selective serotonin reuptake inhibitor (SSRI)
Has Porphyria
Large tattoos in areas to be tested
Pregnancy or nursing
Taking any oral or topical medications that could interfere with the PDT
Active rashes in the areas

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Dayton?

Yes, this clinical trial (NCT06778434) has an active research site in Dayton, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Actinic Keratosis Treatment Options in Dayton, OH

If you're searching for actinic keratosis treatment options in Dayton, OH, this clinical trial (NCT06778434) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Dayton research site is actively enrolling participants for this clinical trial. You'll receive care from experienced actinic keratosis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all actinic keratosis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Dayton, OH