San Francisco, CANCT05266040Now EnrollingIRB Ready

Acute Apical Abscess Clinical Trial in San Francisco, CA

Access cutting-edge acute apical abscess treatment through this clinical trial at a research site in San Francisco. Study-provided care at no cost to qualified participants.

Sponsored by University of California, San Francisco

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Expert Care in San Francisco

Access acute apical abscess specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related acute apical abscess treatment provided free

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Check if you qualify for this acute apical abscess clinical trial in San Francisco, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to San Francisco

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit San Francisco site if eligible
  4. 4Begin participation

About This Acute Apical Abscess Study in San Francisco

The Virus in Endodontics (VE) phase I pilot study for preoperative pain will be analyzed and adjusted for the Phase II clinical trial. The Phase II clinical trial on preoperative pain, postoperative pain, and clinical healing will involve 250 patients. Patients will be recruited from the same pool of participants as the Phase II clinical trial. Preoperative cone beam computed tomography (CBCT) scans will be taken as well as three and six month postoperative CBCT scans. The secondary outcomes form the Phase II randomized clinical trial will be clinical success and visible radiographic healing determined by CBCT images.

Sponsor: University of California, San Francisco

Who Can Participate

Inclusion Criteria

Patient must be ≥ 18-year-old
Patient must be systemically healthy; American Society of Anesthesiologists (ASA) Class I or II
Patient must exhibit clinical evidence of pulp necrosis and acute apical abscess
Patient must present with radiographic
signs of apical disease either by
periapical radiography or cone-beam
computed tomography
Patient consented to receive conventional pulpal debridement, incision and drainage at the end of the study
Persistent pain of moderate or higher level (\>4) was the main inclusion criterion. Pain assessed as follows: 0 defined as no pain, 1-3 as mild pain, 4-6 as moderate pain, and 7-10 as severe pain

Exclusion Criteria

Smokers (more than 10 cigarettes per day)
External or internal tooth resorption
Marginal periodontitis
Pregnant or nursing mothers (hormonal factors may influence the periapical condition)
Documented allergic or adverse reactions to amoxicillin or valacyclovir
Teeth with unusual anatomy or inaccurate clinical diagnosis on the day of treatment (i.e., partially necrotic pulp)
Patients currently taking antibiotics or antiviral medications

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in San Francisco?

Yes, this clinical trial (NCT05266040) has an active research site in San Francisco, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Acute Apical Abscess Treatment Options in San Francisco, CA

If you're searching for acute apical abscess treatment options in San Francisco, CA, this clinical trial (NCT05266040) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our San Francisco research site is actively enrolling participants for this clinical trial. You'll receive care from experienced acute apical abscess specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all acute apical abscess clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · San Francisco, CA