Knoxville, TNNCT07749170Now EnrollingIRB Ready

Acute Ischemic Stroke Clinical Trial in Knoxville, TN

Access cutting-edge acute ischemic stroke treatment through this clinical trial at a research site in Knoxville. Study-provided care at no cost to qualified participants.

Sponsored by Penumbra Inc.

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Expert Care in Knoxville

Access acute ischemic stroke specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related acute ischemic stroke treatment provided free

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Check if you qualify for this acute ischemic stroke clinical trial in Knoxville, TN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Knoxville

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Knoxville site if eligible
  4. 4Begin participation

About This Acute Ischemic Stroke Study in Knoxville

The objective of this study is to collect safety and effectiveness data on the Penumbra System reperfusion catheters in participants with isolated primary non-dominant and distal M2 occlusions who undergo endovascular mechanical thrombectomy (EVT). Additionally, this study aims to observe characteristics and outcomes of participants treated with medical management (MM) alone and those who receive EVT + MM per current medical practice.

Sponsor: Penumbra Inc.

Who Can Participate

Inclusion Criteria

Participant age ≥ 18
Participant experiencing acute ischemic stroke due to a confirmed primary M2 occlusion in the vertical segment or post-bifurcation in the non-dominant or co-dominant branch of the horizontal segment
NIHSS ≥5 or NIHSS 3-4 with disabling symptoms
Pre-stroke mRS 0-1
For participants undergoing thrombectomy: Planned first-line treatment with Penumbra System reperfusion catheters
Informed consent obtained per Institutional Review Board/Ethics Committee requirements

Exclusion Criteria

Any stenosis or occlusion in the ICA origin requiring treatment during the procedure or within the 90-day follow-up period.
Known multiple occlusions
Secondary M2 occlusion
Known or high suspicion of underlying ICAD as the cause of the M2 occlusion
Current hospitalization at time of stroke onset and/or any comorbid disease or condition expected to compromise survival or ability to complete follow-up assessments through 90 days
Currently participating in an investigational (drug, device, etc.) clinical trial that will influence the endovascular procedure or acute treatment. Participants in secondary prevention, observational, natural history and/or epidemiological studies are eligible.
Other medical, behavioral, or psychological conditions that in the opinion of the Investigator could limit the ability to participate in the study, including compliance with follow-up requirements, or that could impact the scientific integrity of the study

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Knoxville?

Yes, this clinical trial (NCT07749170) has an active research site in Knoxville, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Acute Ischemic Stroke Treatment Options in Knoxville, TN

If you're searching for acute ischemic stroke treatment options in Knoxville, TN, this clinical trial (NCT07749170) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Knoxville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced acute ischemic stroke specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all acute ischemic stroke clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Knoxville, TN