NCT07212166 · Memorial Sloan Kettering Cancer Center
A Study of Questionnaires in Adolescents and Young Adults With Cancer
What this study is about
The purpose of this study is to evaluate a questionnaire called PRO-AYA: Patient-Reported Outcomes for Adolescents and Young Adults.
View original scientific description
The purpose of this study is to evaluate a questionnaire called PRO-AYA: Patient-Reported Outcomes for Adolescents and Young Adults.
Interventions
OTHER
Patient-Reported Outcome Surveys
PRO-AYA , Patient-Reported ECOG PS, EORTC QLQ-C30, Demographic/Clinical Characteristics
OTHER
Spanish version of PRO-AYA and the cognitive interview
Revised Spanish PRO-AYA, Demographic/Clinical Characteristics
Primary outcome measures
Test-retest reliability
Time frame: up to one month
The test-retest reliability will be based on the intraclass correlation (ICC) coefficients between the baseline and follow-up domain scores of PRO-AYA.
Linguistically validate PRO-AYA or patients who prefer their healthcare be delivered in Spanish. (Cohort 2)
Time frame: up to a month
The primary goal of these cognitive interviews is to ensure that the wording and/or phrasing of the instructions, questions and answer choices are appropriate for native Spanish-speakers. The wording and phrasing are a result of direct translation of the English version of the PRO-AYA to a Spanish version.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- English- or Spanish proficient o As assessed by two items: How well do you speak English? What is your preferred language for healthcare?
- Between the ages of 15-39
- Diagnosed with cancer or the recurrence of a cancer and/or received active treatment for cancer between the ages of 15-39
- Able to complete questionnaires by themselves or with assistance
- For Cohort 1 ONLY:
- 3 months from last treatment without plan to initiate any form of cancer-directed treatment in the next 3 months OR
- On chronic cancer-directed therapy for the last 3 months without plan to change cancer-directed therapy in the next 3 months AND
- ECOG Performance Status (0-4) or KPS/Lansky Score (0-100)
Where
- Basking Ridge, New Jersey
- Middletown, New Jersey
- Montvale, New Jersey
- Commack, New York
- Harrison, New York
- New York, New York
- Uniondale, New York
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Aug 4, 2026 · Source of record for eligibility and locations