Nashville, TNNCT07427394Now EnrollingIRB Ready

Advanced Breast Cancer Clinical Trial in Nashville, TN

Access cutting-edge advanced breast cancer treatment through this clinical trial at a research site in Nashville. Study-provided care at no cost to qualified participants.

Sponsored by AstraZeneca

Quick Self-Assessment

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Expert Care in Nashville

Access advanced breast cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related advanced breast cancer treatment provided free

Apply for This Nashville Location

Check if you qualify for this advanced breast cancer clinical trial in Nashville, TN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Nashville

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Nashville site if eligible
  4. 4Begin participation

About This Advanced Breast Cancer Study in Nashville

A study to investigate camizestrant in combination with atirmociclib in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer previously treated with a cyclin dependent kinase 4/6 (CDK4/6) inhibitor.

Sponsor: AstraZeneca

Who Can Participate

Inclusion Criteria

Participants with advanced adenocarcinoma of the breast and must have received prior adequate therapy in accordance with local practice for their tumor type and stage of disease.
Metastatic or locoregionally recurrent disease and radiological or objective evidence of progression on or after the last systemic therapy prior to starting investigational medicinal products.
Eastern cooperative oncology group (ECOG)/World Health Organization (WHO) performance status 0 to 1, and a minimum life expectancy of 12 weeks.
At least one lesion that is measurable and/or non-measurable, as per RECIST 1.1 and that can be accurately assessed at baseline and is suitable for repeated assessment by computed tomography (CT), magnetic resonance imaging (MRI), or plain X-ray, or clinical examination.
Menopausal status
Pre-menopausal women must start GnRH agonist therapy at least 4 weeks before study treatment and continue throughout the study.
Post-menopausal women must meet one of these criteria: bilateral oophorectomy, age ≥60 years, age ≥50 years with ≥12 months amenorrhea and intact uterus without hormonal therapy, or age \<60 years with ≥12 months amenorrhea and post-menopausal hormone levels.
Histological or cytological confirmation of adenocarcinoma of the breast.
Participants of childbearing potential must agree to use one highly effective contraceptive measure.
Documentation of ER-positive tumor irrespective of progesterone receptor status. Main

Exclusion Criteria

A participant who has received 2 or more lines of CDK4/6 inhibitors in the advanced disease setting.
A participant who has received prior camizestrant or atirmociclib treatment in the advanced disease setting.
Patients previously treated with other next generation selective estrogen receptor degrader (SERDs) or other experimental ETs in the advanced disease setting.
Patients previously treated with other experimental cyclin-dependent kinase (CDK) inhibitors are not eligible.
Inability to swallow oral medications.
Any unresolved toxicities of Grade ≥ 2 from prior anti-cancer therapy (with the exception of alopecia).
Presence of life-threatening metastatic visceral disease.
Any evidence of severe or uncontrolled systemic diseases.
Contraindication to or known intolerance/hypersensitivity of/to camizestrant or atirmociclib.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Nashville?

Yes, this clinical trial (NCT07427394) has an active research site in Nashville, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Advanced Breast Cancer Treatment Options in Nashville, TN

If you're searching for advanced breast cancer treatment options in Nashville, TN, this clinical trial (NCT07427394) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Nashville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced advanced breast cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all advanced breast cancer clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Nashville, TN