NCT07659158 · Mayo Clinic
Virtual Group Resilient Living Program For Patients Living With Advanced Cancer
What this study is about
This study is a forward-looking, minimal risk, non-randomly assigned, single-treatment group$1 study to determine feasibility and assess effectiveness of a Virtual Group Resilient Living Program (RLP) on anxiety, stress, quality of life (QOL), coping, and fatigue among patients with advanced cancer.
View original scientific description
This study is a prospective, minimal risk, non-randomized, single-arm study to determine feasibility and assess effectiveness of a Virtual Group Resilient Living Program (RLP) on anxiety, stress, quality of life (QOL), coping, and fatigue among patients with advanced cancer. The group RLP is a psychosocial intervention that consists of a total of 7 weekly sessions in which the interventionalist teaches the patients techniques on stress management and building resilience (mindfulness, uplifting emotions, reframe experiences through principles of gratitude, compassion, acceptance, meaning, and forgiveness). The group setting allows for support and connection amongst the patients, providing further support and motivation to practice the principles of the program.
Interventions
BEHAVIORAL
Virtual Group Resilient Living Program (RLP)
The Resilient Living Program (RLP) is a virtual program consisting of online modules and virtual training sessions focused on techniques for managing stress and building resilience (mindful presence, uplifting emotions, and reframing experiences through principles of gratitude, compassion, acceptance, meaning, and forgiveness).
OTHER
Survey Completion
Participants will complete study-related surveys.
Primary outcome measures
Enrollment Feasibility
Time frame: Up to 1 year
Enrollment feasibility will be met if 42 patients are enrolled within a year.
Completion Feasibility
Time frame: Up to 1 year
Completion feasibility will be met if at least 32 of 42 patients (≥75%) enrolled in the intervention arm attend at least 4 of the 7 program sessions.
Acceptability - Was it Worth it (WIWI)
Time frame: After week 7 session
measured by the three item responses from the Was It Worth It (WIWI) questionnaire. Acceptability will be met if at least 75% of respondents answer "Yes" to at least two out of the three items
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- English fluency
- Diagnosis of advanced (stage III/IV) malignancy
- Baseline distress score ≥ 4/10. Patients can answer questions orally rather than complete worksheet, if applicable
- Life expectancy of ≥ 6 months
- Provide informed consent
- Ability to complete questionnaire(s) by themselves or with assistance
- Has a reliable internet connection
- Has the ability to utilize technology to watch online modules, \& participate in virtual sessions
Exclusion criteria
- As determined through self-report, those diagnosed with a history of a psychotic episode ≤ 5 years
- All psychological co-morbidities such as a history of untreated schizophrenia, \& bipolar disease
- A diagnosis of severe cognitive impairment
Where
- Rochester, Minnesota
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jul 2, 2026 · Source of record for eligibility and locations