Dallas, TXNCT07337525Now EnrollingIRB Ready

Advanced Malignant Solid Tumor Clinical Trial in Dallas, TX

Access cutting-edge advanced malignant solid tumor treatment through this clinical trial at a research site in Dallas. Study-provided care at no cost to qualified participants.

Sponsored by Pilatus Biosciences Inc

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Expert Care in Dallas

Access advanced malignant solid tumor specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related advanced malignant solid tumor treatment provided free

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Check if you qualify for this advanced malignant solid tumor clinical trial in Dallas, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Dallas

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Dallas site if eligible
  4. 4Begin participation

About This Advanced Malignant Solid Tumor Study in Dallas

The goal of this clinical trial is to learn about what doses of PLT012 are safe to use in adults with advanced cancers in solid tumors. It will also learn about how effective different doses of PLT012 are in treating cancer. The main questions it aims to answer are: What adverse events and toxicities (harmful side effects) are associated with different doses of PLT012? What are the blood levels of PLT012 in your body at different timepoints? What effect does PLT012 have on reducing tumor size and/or preventing the worsening of cancer? All participants will receive PLT012 and none will receive placebo (a look-alike substance that contains no drug). Participants will receive PLT012 by intravenous infusion once every 3 weeks. Treatment with PLT012 can continue until the participant's disease worsens or they cannot tolerate treatment. For the first 12 weeks, visits to the clinic will be more frequent (from 1 to 5 times over a 3-week period). After the first 12 weeks, visits will be reduced to once every 3 weeks.

Sponsor: Pilatus Biosciences Inc

Who Can Participate

Inclusion Criteria

Aged at least 18 years and provided written informed consent
Histologically or cytologically confirmed advanced solid tumors (except primary CNS malignancies)
Has at least one measurable lesion per RECIST v1.1
ECOG PS of 0 to 1
Life expectancy of ≥ 12 weeks
Child-Pugh score of Class A (for hepatocellular carcinoma only)
Adequate organ function as defined by protocol-specified laboratory values
Not pregnant or breastfeeding

Exclusion Criteria

Insufficient washout period from prior therapies as defined in the study protocol
Ongoing Grade 2 or higher toxicities from prior treatments (with some exceptions)
Concurrent or recent (within 2 years) malignancy other than the disease under study (with some exceptions)
Uncontrolled HIV, uncontrolled hepatitis B, or uncontrolled acute hepatitis C infections
Unstable/uncontrolled or untreated central nervous system (CNS) metastasis
Active or recent (within 3 years) autoimmune disease requiring medical treatment
Recipient of any organ transplant including allogeneic stem-cell transplant
Clinically significant and active cardiovascular disease
Known active alcohol or drug abuse
Psychiatric disorders that would prohibit the understanding of the Informed Consent Form
Ascites requiring therapeutic paracentesis or hepatic encephalopathy requiring medical interventions within the past 6 months (if hepatocellular carcinoma)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Dallas?

Yes, this clinical trial (NCT07337525) has an active research site in Dallas, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Advanced Malignant Solid Tumor Treatment Options in Dallas, TX

If you're searching for advanced malignant solid tumor treatment options in Dallas, TX, this clinical trial (NCT07337525) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Dallas research site is actively enrolling participants for this clinical trial. You'll receive care from experienced advanced malignant solid tumor specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all advanced malignant solid tumor clinical trials near you to find additional studies recruiting in your area.

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See all advanced solid tumors clinical trials recruiting in Dallas — not just this study.

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Secure · Expert Care · Dallas, TX