Sarasota, FLNCT07189403Now EnrollingIRB Ready

Advanced or Metastatic Adrenocortical Carcinoma Clinical Trial in Sarasota, FL

Access cutting-edge advanced or metastatic adrenocortical carcinoma treatment through this phase 1 clinical trial at a research site in Sarasota. Study-provided care at no cost to qualified participants.

Sponsored by Daiichi Sankyo

Quick Self-Assessment

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Expert Care in Sarasota

Access advanced or metastatic adrenocortical carcinoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related advanced or metastatic adrenocortical carcinoma treatment provided free

Apply for This Sarasota Location

Check if you qualify for this advanced or metastatic adrenocortical carcinoma clinical trial in Sarasota, FL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Sarasota

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Sarasota site if eligible
  4. 4Begin participation

About This Advanced or Metastatic Adrenocortical Carcinoma Study in Sarasota

This FIH study is designed to assess the safety, tolerability, and preliminary efficacy signals of DS9051b in participants with ACC and mCRPC.

Sponsor: Daiichi Sankyo

Who Can Participate

Inclusion Criteria

for All Participants
Sign and date the main ICF, prior to the start of any trial-specific procedures.
Adults ≥18 years of age at the time the ICF is signed (Follow local regulatory requirements if the legal age of consent for trial participation is \>18 years old)
Histologically confirmed diagnosis of ACC or adenocarcinoma of the prostate
ECOG PS of 0 or 1 assessed no more than 14 days prior to C1D1. (ECOG PS of 2 due to cancer pain is acceptable)
Has adequate organ and bone marrow function as assessed by local laboratory within 14 days prior to C1D1 as defined below. Organ and bone marrow function criteria must also be met when laboratory tests are repeated within 3 days of initiation of trial intervention as appropriate. Additional Inclusion Criteria for Participants with mCRPC
Treatment with at least 1 line (or more) of ARPI therapy for CSPC or in CRPC for a minimum of 12 weeks (eg, abiraterone, enzalutamide, darolutamide, apalutamide).
Treatment with at least 1 line (or more) of chemotherapy, having ineligibility for chemotherapy or refusal of chemotherapy.
Documented disease progression by one or more of the following criteria:
PSA progression as defined by PCWG3 criteria.
Soft tissue disease progression as defined by RECIST 1.1 criteria.
Bone disease progression as defined by Prostate Cancer Working Group 3 criteria. An individual who meets any of the following criteria will be excluded from participation in this trial:
History of pituitary gland dysfunction.
Active or uncontrolled autoimmune disease requiring systemic treatment.
Any medical condition (other than the cancer disease) requiring a dose of concurrent systemic corticosteroid treatment greater than 5 mg of prednisone and/or 100 μg of fludrocortisone per day (or equivalent).
Active infection or other medical conditions that would make corticosteroids contraindicated.
Has spinal cord compression or clinically active central nervous system metastases, defined as untreated, clinically progressive, symptomatic, or requiring systemic therapy with corticosteroids or anticonvulsants or local therapy (ie, radiotherapy) to control associated symptoms.
Uncontrolled or significant cardiovascular disease.
History of another primary malignancy (beyond the indication\[s\] under study) except for:
Malignancy treated with curative intent and with no known active disease ≥3 years before the first dose of trial intervention and of low potential risk for recurrence.
Non-melanoma skin cancer, lentigo maligna, or lentigo maligna melanoma treated with curative intent and without evidence of disease.
Carcinoma in situ treated with curative intent and without evidence of disease.
Participants with a history of prostate cancer (tumor/node/metastasis stage) of Stage ≤T2cN0M0 without biochemical recurrence or progression and who, in the opinion of the investigator, are not deemed to require active intervention.
Unresolved toxicities from previous anticancer therapy, defined as toxicities (other than alopecia) not yet resolved to NCI-CTCAE version 5.0, Grade ≤1 or baseline.
Participants who cannot swallow whole DS9051b tablets and/or follow DS9051b administration schedule at protocol-defined frequency due to some reasons (eg, dysphagia etc).
Known gastrointestinal disease or gastrointestinal procedure that may interfere with absorption of trial intervention including proton pump inhibitors and antacids.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Sarasota?

Yes, this clinical trial (NCT07189403) has an active research site in Sarasota, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Advanced or Metastatic Adrenocortical Carcinoma Treatment Options in Sarasota, FL

If you're searching for advanced or metastatic adrenocortical carcinoma treatment options in Sarasota, FL, this clinical trial (NCT07189403) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Sarasota research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced advanced or metastatic adrenocortical carcinoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all advanced or metastatic adrenocortical carcinoma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Sarasota, FL