Goodyear, AZNCT06545942Now EnrollingIRB Ready

Advanced Solid Tumor Clinical Trial in Goodyear, AZ

Access cutting-edge advanced solid tumor treatment through this phase 1 clinical trial at a research site in Goodyear. Study-provided care at no cost to qualified participants.

Sponsored by MOMA Therapeutics

Quick Self-Assessment

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Expert Care in Goodyear

Access advanced solid tumor specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related advanced solid tumor treatment provided free

Apply for This Goodyear Location

Check if you qualify for this advanced solid tumor clinical trial in Goodyear, AZ

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Goodyear

    Convenient for AZ residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Goodyear site if eligible
  4. 4Begin participation

About This Advanced Solid Tumor Study in Goodyear

This Phase 1, multi-center, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and preliminary clinical activity of MOMA-313 administered orally as a single agent or combination therapy in patients with homologous recombinant deficient solid tumors.

Sponsor: MOMA Therapeutics

Who Can Participate

Inclusion Criteria

Age ≥ 18 years
Have histologically confirmed disease for each treatment arm as follows:
Treatment Arm 1 (MOMA-313 Monotherapy) \- Advanced (including locally), relapsed or metastatic solid tumors that are not eligible for curative therapy, with any HR-deficient alteration.
Treatment Arm 2 (MOMA-313 in Combination with Olaparib):
Dose escalation: Advanced (including locally), relapsed or metastatic solid tumors that are not eligible for curative therapy, for which a PARP inhibitor is indicated, with select HR-deficient mutations. Patients may be PARP inhibitor naive or exposed.
Dose optimization: Advanced (including locally), relapsed or metastatic CRPC or pancreatic ductal adenocarcinoma (PDAC) with select HR-deficient mutations. Patients must be PARP inhibitor naive.
Have at least 1 lesion at baseline (measurable or non-measurable) suitable for repeat imaging evaluation by RECIST and/or PCWG-3
ECOG PS ≤ 2
Fully recovered from clinically relevant effects of prior therapy, radiotherapy, and/or surgery \*\*hormonal therapy allowed. Palliative radiotherapy allowed.
Adequate organ function per local labs
Comply with contraception requirements
Written informed consent must be obtained according to local guidelines Key

Exclusion Criteria

Active prior or concurrent malignancy (some exceptions allowed)
Clinically relevant cardiovascular disease
Known CNS metastasis associated with progressive neurological symptoms (stable doses of corticosteroids allowed)
Known active infection
Prior polymerase theta inhibitor exposure
Known allergy, hypersensitivity, and/or intolerance to MOMA-313
Olaparib exposed patients with known hypersensitivity to PARP inhibitors (for patients considered for olaparib only)
Impaired GI function that may impact absorption.
Patient is pregnant or breastfeeding.
Known to be HIV positive, unless all of the following criteria are met:
Undetectable viral load or CD4+ count ≥300 cells/μL
Receiving highly active antiretroviral therapy
No AIDS-related illness within the past 12 months
Active liver disease (some exceptions are allowed)
Prior or ongoing condition, therapy, or laboratory abnormality that, in the investigator's opinion, may affect safety of the patient, confound the results of the study, and/or interfere with the patients participation in the study

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Goodyear?

Yes, this clinical trial (NCT06545942) has an active research site in Goodyear, AZ that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Advanced Solid Tumor Treatment Options in Goodyear, AZ

If you're searching for advanced solid tumor treatment options in Goodyear, AZ, this clinical trial (NCT06545942) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Goodyear research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced advanced solid tumor specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all advanced solid tumor clinical trials near you to find additional studies recruiting in your area.

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