San Antonio, TXNCT07182591Now EnrollingIRB Ready

Advanced Solid Tumor Clinical Trial in San Antonio, TX

Access cutting-edge advanced solid tumor treatment through this phase 1 clinical trial at a research site in San Antonio. Study-provided care at no cost to qualified participants.

Sponsored by Daiichi Sankyo

Quick Self-Assessment

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Preparing your pre-screening questions…

Expert Care in San Antonio

Access advanced solid tumor specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related advanced solid tumor treatment provided free

Apply for This San Antonio Location

Check if you qualify for this advanced solid tumor clinical trial in San Antonio, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to San Antonio

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit San Antonio site if eligible
  4. 4Begin participation

About This Advanced Solid Tumor Study in San Antonio

This study aims to assess the safety, tolerability, and preliminary efficacy and to determine the MTD of DS5361b in monotherapy and combination with pembrolizumab in participants with advanced or metastatic solid tumors.

Sponsor: Daiichi Sankyo

Who Can Participate

Inclusion Criteria

The clinical site will screen for the full inclusion criteria per protocol.
Adults ≥18 years of age at the time the ICF is signed (Please follow local regulatory requirements if the legal age of consent for trial participation is \>18 years old).
Has histologically- or cytologically documented recurrent, metastatic, or unresectable solid tumors that are refractory to or intolerable with standard treatment or for which no standard treatment is available (For Part 1 and Part 2 only).
Participants need to have documented TMB or MSI status using a validated or approved genomic test as per applicable regulations prior to Cycle 1 Day 1. In Part 1 and Part 2, participants need to have documented TMB-H and/or MSI-H status. In Part 3, participants need to have documented TMB-H status.
Has measurable disease based on local CT/MRI imaging as assessment by the investigator using RECIST v1.1.
Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-1.
Has adequate organ and bone marrow function as assessed by local laboratory within 14 days prior to initiation of trial intervention.
For HNSCC participants only: have documented results from local testing of HPV for oropharyngeal cancer. If HPV status has previously been tested using this procedure, no retesting is required. Dose Expansion (Part 3) Only:
Has histologically or cytologically confirmed, Stage IV NSCLC without actionable gene alteration.
No prior systemic therapy.
Participants with PD-L1 TPS ≥1%.
Has histologically or cytologically confirmed recurrent or metastatic HNSCC that is considered incurable by local therapies.
No prior systemic therapy administered in the recurrent or metastatic setting.
Participants with PD-L1 CPS ≥1. Key

Exclusion Criteria

Has spinal cord compression or clinically active central nervous system metastases.
Has a history of leptomeningeal carcinomatosis.
Uncontrolled or significant cardiovascular disease.
Any of the following within the past 6 months prior to enrollment: cerebrovascular accident, transient ischemic attack, or other arterial thromboembolic event.
Has a history of (noninfectious) interstitial lung disease (ILD)/pneumonitis that required corticosteroids, has current ILD/pneumonitis, or where suspected ILD/pneumonitis cannot be ruled out.
Clinically severe pulmonary compromise (ie, requiring any supplemental oxygen).
Has any evidence of severe or uncontrolled systemic diseases.
Has active or uncontrolled HBV infection. Hepatitis B SCR testing is required.
Has active or uncontrolled HCV infection. Hepatitis C SCR testing is required.
For the dose escalation phase (Part 1 and Part 2), has HIV infection. For the dose expansion part (Part 3), has active or uncontrolled HIV infection.
Prior organ transplantation, including allogeneic stem cell transplantation.
Has an active, known, or suspected autoimmune disease.
Has a diagnosis of immunodeficiency or is receiving systemic steroid therapy or any other form of immunosuppressive therapy within 14 days prior to the trial intervention.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in San Antonio?

Yes, this clinical trial (NCT07182591) has an active research site in San Antonio, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Advanced Solid Tumor Treatment Options in San Antonio, TX

If you're searching for advanced solid tumor treatment options in San Antonio, TX, this clinical trial (NCT07182591) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our San Antonio research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced advanced solid tumor specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all advanced solid tumor clinical trials near you to find additional studies recruiting in your area.

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