Houston, TXNCT07767474Now EnrollingIRB Ready

Advanced Solid Tumors Clinical Trial in Houston, TX

Access cutting-edge advanced solid tumors treatment through this phase 1/2 clinical trial at a research site in Houston. Study-provided care at no cost to qualified participants.

Sponsored by Antares Therapeutics, Inc

Quick Self-Assessment

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Expert Care in Houston

Access advanced solid tumors specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related advanced solid tumors treatment provided free

Apply for This Houston Location

Check if you qualify for this advanced solid tumors clinical trial in Houston, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Houston

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Houston site if eligible
  4. 4Begin participation

About This Advanced Solid Tumors Study in Houston

Study ATX-898-101 is a phase 1/2 open-label study evaluating the safety, tolerability, pharmacokinetic, and preliminary efficacy of ATX-898 as monotherapy and in combination with anti-neoplastic agents in selected solid tumors. This study consists of 2 parts. Part 1 evaluates ATX-898 as monotherapy and Part 2 evaluates ATX-898 in combination with anti-neoplastic agents of interest. Both parts will consists of a dose escalation portion and a dose expansion portion.

Sponsor: Antares Therapeutics, Inc

Who Can Participate

Inclusion Criteria

Has histologically or cytologically confirmed advanced solid tumor malignancy that is metastatic or locally advanced and unresectable
Is ≥18 years of age at the time of signing the informed consent form
ECOG performance status score of 0 or 1
Adequate organ function
Must consent to a pre-treatment tumor biopsy (collected during screening or have available archival tumor tissue in the past 5 years. For Part 1a (monotherapy dose escalation)
Has received one or more standard systemic therapies and additional standard therapies are either not available, or participant ineligible for available standard therapies For Part 1b (monotherapy dose expansion)
b1: Has platinum-resistant or refractory metastatic ovarian cancer
b2: Has recurrent or metastatic gynecologic cancer excluding the cancers eligible for b1
b3: Has recurrent advanced or metastatic solid tumor excluding the cancers eligible for b1 or b2
Has at least 1 measurable lesion per RECIST 1.1 For Part 2a (combination dose escalation)
Has confirmed HR+ HER2 - (including HER2 low and ultra low) status
Has received prior therapy in the metastatic For Part 2b (combination dose expansion)
Has confirmed HR+ HER2 - (including HER2 low and ultra low) status
Treatment-naïve or has received prior therapy in the metastatic setting

Exclusion Criteria

Has history (within ≤2 years before screening) of a solid tumor or hematological malignancy that is histologically distinct from the cancer being studied
Has symptomatic CNS metastases at screening or asymptomatic CNS metastases requiring corticosteroids to control symptoms within 28 days prior to the first dose of ATX-898.
Has toxicities from previous anticancer therapies that have not resolved to baseline levels or to CTCAE Grade ≤1, with the exception of alopecia any grade and Grade ≤2 peripheral neuropathy
Has any condition for which, in the opinion of the Investigator, participation would not be in the best interest of the participant or would prevent, limit, or confound the protocol-specified assessments Cohort Specific:
For abemaciclib cohorts only: has a history of any events of cardiac etiology that would contraindicate dosing with abemaciclib
For ribocicilib only: has history of pneumonitis or interstitial lung disease

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT07767474) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Advanced Solid Tumors Treatment Options in Houston, TX

If you're searching for advanced solid tumors treatment options in Houston, TX, this clinical trial (NCT07767474) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced advanced solid tumors specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all advanced solid tumors clinical trials near you to find additional studies recruiting in your area.

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