Fairfax, VANCT07141706Now EnrollingIRB Ready

Advanced/Metastatic Solid Tumors Clinical Trial in Fairfax, VA

Access cutting-edge advanced/metastatic solid tumors treatment through this clinical trial at a research site in Fairfax. Study-provided care at no cost to qualified participants.

Sponsored by DualityBio Inc.

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Expert Care in Fairfax

Access advanced/metastatic solid tumors specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related advanced/metastatic solid tumors treatment provided free

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Check if you qualify for this advanced/metastatic solid tumors clinical trial in Fairfax, VA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Fairfax

    Convenient for VA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Fairfax site if eligible
  4. 4Begin participation

About This Advanced/Metastatic Solid Tumors Study in Fairfax

This is a multicenter, open-label, multiple-dose, FIH Phase 1a/1b study. Phase 1a adopts an accelerated titration design and a BOIN design to identify the MTD or MAD of DB-1317; Phase 1b includes up to 3 randomized dose expansion cohorts to further evaluate the safety, tolerability and preliminary efficacy of DB-1317 in selected solid tumors and to identify optimal RP2D.

Sponsor: DualityBio Inc.

Who Can Participate

Inclusion Criteria

Male or female adults
Unresectable advanced or metastatic selected solid tumors that have relapsed or progressed on or after standard systemic treatments.
Only applicable to backfilling participants in Phase 1a and participants in Phase 1b: At least one measurable lesion as assessed by the investigator according to RECIST version 1.1 criteria. Participants with non-measurable disease are allowed for CRPC participants.
Has a life expectancy of ≥ 3 months.
Has an ECOG PS of 0-1.
Has LVEF ≥ 50% within 28 days before enrollment.
Is willing to provide pre-existing resected tumor samples or undergo fresh tumor biopsy for the measurement of ADAM9 expression level and other biomarkers if no contra-indication.
Male and female participants of reproductive/childbearing potential must agree to use adequate contraceptive methods Key

Exclusion Criteria

Prior treatment with ADAM9 targeted therapy.
Prior treatment with antibody-drug conjugate with topoisomerase I inhibitor.
Has a medical history of symptomatic congestive heart failure or serious cardiac arrhythmia requiring treatment.
Has a medical history of myocardial infarction or unstable angina within 6 months before enrollment.
Has any clinically important abnormalities in rhythm, conduction or morphology of resting ECG
Has an average of Fredericia's formula-QT corrected interval (QTcF) prolongation to \> 470 ms in males and females
Has a history of (non-infectious) ILD/pneumonitis
Has a lung-specific intercurrent clinically significant illness
Has an uncontrolled infection requiring intravenous injection of antibiotics, antivirals, or antifungals.
Known human immunodeficiency virus (HIV) infection;Chronic, active, or uncontrolled hepatitis B;
Known chronic, active, or uncontrolled hepatitis C
Has clinically significant corneal disease.
Has clinically active brain metastases
Has unresolved toxicities from previous anticancer therapy Concurrent malignancy \< 3 years. NOTE: Other protocol defined Inclusion/Exclusion criteria may apply.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Fairfax?

Yes, this clinical trial (NCT07141706) has an active research site in Fairfax, VA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Advanced/Metastatic Solid Tumors Treatment Options in Fairfax, VA

If you're searching for advanced/metastatic solid tumors treatment options in Fairfax, VA, this clinical trial (NCT07141706) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Fairfax research site is actively enrolling participants for this clinical trial. You'll receive care from experienced advanced/metastatic solid tumors specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all advanced/metastatic solid tumors clinical trials near you to find additional studies recruiting in your area.

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