NCT03848663 · University of Minnesota
Visual Remapping to Aid Reading With Field Loss
What this study is about
Reading performance in patients with Central Vision Loss and age matched controls with artificial scotomas will be measured with and without different kinds of remapping of missing text to different parts of the visual field.
View original scientific description
Reading performance in patients with Central Vision Loss and age matched controls with artificial scotomas will be measured with and without different kinds of remapping of missing text to different parts of the visual field.
Interventions
BEHAVIORAL
Traditional Remapping
Shifting text outside of scotoma
BEHAVIORAL
Personalized Remapping
Shifting text based on individual letter-based perimetry
Primary outcome measures
Reading Speed for Individual Words
Time frame: Measured during third visit- each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
How quickly participants can correctly read displayed text
Reading Speed for Sentences
Time frame: Measured during fourth visit- each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
How quickly participants can correctly read displayed text
Reading Speed for Natural Text Samples
Time frame: Measured during fifth visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
How quickly participants can correctly read displayed text
Reading error rate for Individual Words
Time frame: Measured during third visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
How many mistakes participants make
Reading error rate for Sentences
Time frame: Measured during fourth visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
How many mistakes participants make
Reading error rate for Natural Text Samples
Time frame: Measured during fifth visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
How many mistakes participants make
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- 16 years or older
- Central vision loss of at least 5 deg diameter, including the fovea, from bilateral central scotomas
- Stable fixation (+/- 1 deg) using their PRL.
- No cognitive impairment as indicated by a Mini-Mental State Examination (MMSE).
- Satisfactory calibration achievable using eye tracker
Exclusion criteria
- Central vision loss of less than 5 deg diameter; scotomas that do not cover the fovea; unilateral scotomas
- Poor fixation (worse than+/- 1 deg) using their PRL.
- Cognitive impairment as indicated by a Mini-Mental State Examination (MMSE).
- Satisfactory calibration not achievable using eye tracker
Where
- Minneapolis, Minnesota
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jul 8, 2026 · Source of record for eligibility and locations