Aurora, CONCT05498116Now EnrollingIRB Ready

Albuminuria Clinical Trial in Aurora, CO

Access cutting-edge albuminuria treatment through this phase 4 clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by University of Colorado, Denver

Quick Self-Assessment

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Expert Care in Aurora

Access albuminuria specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related albuminuria treatment provided free

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Check if you qualify for this albuminuria clinical trial in Aurora, CO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This Albuminuria Study in Aurora

Kidney disease is a common problem among people with type 1 diabetes and can lead to disability, dialysis, and early death. Inflammation plays a key role in the development of kidney disease in type 1 diabetes and targeting leukotrienes, inflammatory chemicals the body releases in response to allergic reactions, may represent a promising therapy to slow the progression of diabetic kidney disease. The current proposal will investigate whether montelukast, a leukotriene blocker, lowers increased levels of protein in the urine (an early marker of diabetic kidney disease), and improves kidney and cardiovascular function in people with type 1 diabetes and kidney disease.

Sponsor: University of Colorado, Denver

Who Can Participate

Inclusion Criteria

Age 18-80 years
Type 1 diabetes for at least 5 years
Urine albumin to creatinine ratio 30-5000 mg/g on first morning void
eGFR 30-89 ml/min/1.73m2 at time of screening
Blood pressure \<140/90 mm Hg prior to randomization
Use of angiotensin converting enzyme inhibitor or angiotensin receptor blocker with stable dose for 4 weeks
BMI \< 40 kg/m2 (FMDBA measurements can be inaccurate in severely obese patients).
Stable anti-hypertensive regimen for at least one month prior to randomization
Stable regimen of insulin delivery, i.e. automated insulin delivery (AID) system or multiple daily injections) 4 weeks prior to randomization
Sedentary or recreationally active (≤2 days of vigorous aerobic exercise as vigorous exercise may affect vascular function measurements)
Able to provide consent

Exclusion Criteria

Significant comorbid conditions that lead the investigator to conclude that life expectancy is less than 1 year
Uncontrolled hypertension
Factors judged to limit adherence to interventions
Anticipated initiation of dialysis or kidney transplantation within 6 months
Current participation in another research study
Pregnancy or planning to become pregnant or currently breastfeeding
Allergy to aspirin
Severe hepatic impairment (Child-Pugh Class C)
History of major psychiatric disorder
Use of inhaled or systemic corticosteroids or long-acting beta agonists (higher risk of neuropsychiatric reaction)
Penicillin allergy
Iodine allergy
Shellfish allergy
Current use of phenobarbital, rifampin or carbamazepine

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT05498116) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Albuminuria Treatment Options in Aurora, CO

If you're searching for albuminuria treatment options in Aurora, CO, this clinical trial (NCT05498116) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced albuminuria specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all albuminuria clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Aurora, CO